Entrez gene ID | | 3552 |
Official gene symbol | | IL1A |
Full name | | interleukin 1, alpha |
Aliases | | ,IL-1A,IL1,IL1-ALPHA,IL1F1, |
Gene summary | | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q14 |
Gene position | | 113542971 - 113531492 Map Viewer |
Gene orientation | | minus |
Gene size | | 11480 bp |
Gene sequence |
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OMIM ID | | 147760 |
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