Entrez gene ID | | 3559 |
Official gene symbol | | IL2RA |
Full name | | interleukin 2 receptor, alpha |
Aliases | | ,CD25,IDDM10,IL2R,TCGFR, |
Gene summary | | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq] |
Location | | Chromosome: 10 Locus: 10p15-p14 |
Gene position | | 6104333 - 6052657 Map Viewer |
Gene orientation | | minus |
Gene size | | 51677 bp |
Gene sequence |
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OMIM ID | | 147730 |
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