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Gene information for IL2RA (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3559
Official gene symbolIL2RA
Full nameinterleukin 2 receptor, alpha
Aliases,CD25,IDDM10,IL2R,TCGFR,
Gene summaryThe interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq]
LocationChromosome: 10   Locus: 10p15-p14
Gene position6104333 - 6052657  Map Viewer
Gene orientationminus
Gene size51677 bp
Gene sequence
OMIM ID147730