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Gene information for IL2RB (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3560
Official gene symbolIL2RB
Full nameinterleukin 2 receptor, beta
Aliases,CD122,P70-75,
Gene summaryThe interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q13|22q13.1
Gene position37545962 - 37521878  Map Viewer
Gene orientationminus
Gene size24085 bp
Gene sequence
OMIM ID146710