Entrez gene ID | | 3560 |
Official gene symbol | | IL2RB |
Full name | | interleukin 2 receptor, beta |
Aliases | | ,CD122,P70-75, |
Gene summary | | The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq] |
Location | | Chromosome: 22 Locus: 22q13|22q13.1 |
Gene position | | 37545962 - 37521878 Map Viewer |
Gene orientation | | minus |
Gene size | | 24085 bp |
Gene sequence |
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OMIM ID | | 146710 |
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