Entrez gene ID | | 3605 |
Official gene symbol | | IL17A |
Full name | | interleukin 17A |
Aliases | | ,CTLA8,IL-17,IL-17A,IL17, |
Gene summary | | The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6p12 |
Gene position | | 52051185 - 52055436 Map Viewer |
Gene orientation | | plus |
Gene size | | 4252 bp |
Gene sequence |
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OMIM ID | | 603149 |
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