Entrez gene ID | | 3620 |
Official gene symbol | | IDO1 |
Full name | | indoleamine 2,3-dioxygenase 1 |
Aliases | | ,IDO,INDO, |
Gene summary | | Gamma-interferon (IFNG; MIM 147570) has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and Chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase (INDO; EC 1.13.11.52). This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine.[supplied by OMIM] |
Location | | Chromosome: 8 Locus: 8p12-p11 |
Gene position | | 39771328 - 39785950 Map Viewer |
Gene orientation | | plus |
Gene size | | 14623 bp |
Gene sequence |
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OMIM ID | | 147435 |
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