Entrez gene ID | | 3675 |
Official gene symbol | | ITGA3 |
Full name | | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
Aliases | | ,CD49C,FLJ34631,FLJ34704,GAP-B3,GAPB3,MSK18,VCA-2,VL3A,VLA3a, |
Gene summary | | The protein encoded by this gene belongs to the family of integrins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, and function as cell surface adhesion molecules. This gene encodes alpha 3 subunit, which undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 subunit to form an integrin that interacts with many extracellular-matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q21.33 |
Gene position | | 48133340 - 48167849 Map Viewer |
Gene orientation | | plus |
Gene size | | 34510 bp |
Gene sequence |
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OMIM ID | | 605025 |
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