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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ITPKA (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3706
Official gene symbolITPKA
Full nameinositol 1,4,5-trisphosphate 3-kinase A
Aliases,IP3-3KA,IP3KA,
Gene summaryRegulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region. [provided by RefSeq]
LocationChromosome: 15   Locus: 15q14-q21
Gene position41786122 - 41795747  Map Viewer
Gene orientationplus
Gene size9626 bp
Gene sequence
OMIM ID147521