Entrez gene ID | | 3786 |
Official gene symbol | | KCNQ3 |
Full name | | potassium voltage-gated channel, KQT-like subfamily, member 3 |
Aliases | | ,BFNC2,EBN2,KV7.3, |
Gene summary | | The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8q24 |
Gene position | | 133493004 - 133141256 Map Viewer |
Gene orientation | | minus |
Gene size | | 351749 bp |
Gene sequence |
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OMIM ID | | 602232 |
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