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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KCNQ3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3786
Official gene symbolKCNQ3
Full namepotassium voltage-gated channel, KQT-like subfamily, member 3
Aliases,BFNC2,EBN2,KV7.3,
Gene summaryThe M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). [provided by RefSeq]
LocationChromosome: 8   Locus: 8q24
Gene position133493004 - 133141256  Map Viewer
Gene orientationminus
Gene size351749 bp
Gene sequence
OMIM ID602232