Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KRAS (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3845
Official gene symbolKRAS
Full namev-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Aliases,C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KI-RAS,KRAS1,KRAS2,NS,NS3,RASK2,
Gene summaryThis gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq]
LocationChromosome: 12   Locus: 12p12.1
Gene position25403854 - 25358180  Map Viewer
Gene orientationminus
Gene size45675 bp
Gene sequence
OMIM ID190070