Entrez gene ID | | 3845 |
Official gene symbol | | KRAS |
Full name | | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog |
Aliases | | ,C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KI-RAS,KRAS1,KRAS2,NS,NS3,RASK2, |
Gene summary | | This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12p12.1 |
Gene position | | 25403854 - 25358180 Map Viewer |
Gene orientation | | minus |
Gene size | | 45675 bp |
Gene sequence |
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OMIM ID | | 190070 |
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