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Gene information for KRT4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3851
Official gene symbolKRT4
Full namekeratin 4
Aliases,CK4,CYK4,FLJ31692,K4,
Gene summaryThe protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q12-q13
Gene position53208335 - 53200333  Map Viewer
Gene orientationminus
Gene size8003 bp
Gene sequence
OMIM ID123940