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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTX4 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 390667 Official gene symbol PTX4 Full name pentraxin 4, long Aliases ,C16orf38, Gene summary PTX4 belongs to the pentraxin (PTX) superfamily of multifunctional conserved proteins. Pentraxins are characterized by a cyclic multimeric structure and a conserved C-terminal pentraxin domain of approximately 200 amino acids. All pentraxins have a conserved 8-amino acid sequence, HxCxS/TWxS, in which x is any amino acid, within their pentraxin domain. Pentraxins are divided into short proteins, such as C-reactive protein (CRP; MIM 123260) and serum amyloid P protein (APCS; MIM 104770), and long proteins, such as PTX3 (MIM 602492) and PTX4. Some PTXs are part of the humoral arm of innate immunity and behave as functional ancestors of antibodies by mediating agglutination, complement activation, and opsonization (summary by Martinez de la Torre et al., 2010 [PubMed 20357257]).[supplied by OMIM] Location Chromosome: 16   Locus: 16p13.3 Gene position 1538468 - 1535940  Map Viewer Gene orientation minus Gene size 2529 bp Gene sequence >PTX4:complement(1475940..1478468):Length=2529 ATGGGGAGTGGAAACTGGGAGGTCACAGGTCCACCTTGTGGCAGTCGGTGTGAACGGCCT CCCGGACTCCCACGCGGGGTCCACGGACAGTTCCGGAGTGCTGTGGGCCTGTCGGGCCTG CGCTGGGTGCTTCCTGTTTGGGCCTCGTAAAGCACTCATGAGGCCACCCTGCCGTCCCCT GCTCACAGGCAGGAGCTGGAATCACGAGGGAAAGTGACTTGCCGGTGGTTATGGGGTGAG CGGTGGGGATCAGAGCCCCAGCTGTGGGCCTGGAGTCCACACCCCACGTGGTGCAGCTGC ATGGCCTGGGGTCAGTCCCTGGCACCCACCACATCTCACGGCATCGCAGTGGGGATCAAA TCGGTGGGCAGATAGCCAGTGCTGGCCGTGGCCCGGGCACGCGGCCGCTGCTCCCAACTT GAGAGGGCAAAGCCTTTCCCGTCCCGCCCAGCCGGCCCGGCCCGGCCCGCCCCATCATCA CCGTGTCCTCCTTACAGTTCCGGAGATTCCAGGAGGTGACCTGGACACACCTGCAGAACA TCGCCAGCAACTACAACGTGTCCTACAACGTTGACGTCCGGTTCCGGAGCCTGGCGGAAG AGAGCCAGGCTGTGGCTCAGGCAGTCAACCGGTCACAGGCCTCGGTGCAGGGGGAGCTGG CGCAGCTCAAGGCCTGGGTGAGGAAGCTGCAGCGCCGAGGCCGGAAAGTAGACACGCGGC TGCGGGCCTTGGACCTCACCCTGGGCGAGAGGAGCCAGCAGCGGGCCCGGGAAAGGAAGG CACACAAGGCCCAGAGGGACGCCCTGCAGGACTCACTGGCACGCCTGGAGGGCCTCGTCC ACAGCCAGGGCGCCAGGCTGGCTGCTCTGGAGGGGCGGCTGCCCGTGGCCCACCCTGGCA CTGCAGCCCTCGGGCCGGCCCTGGTCCCAACCCCAACCCAGCCTGAGGAGCTGGGCCCGA CCTCCCTGAAGCTTCAGAGGGACAGGCAGGAGCTCCGAGCTGCCTCTGAGCACAGGGGCC CCCCACAGGACTCCTCGGCCCCTCTCCAAGGGAGGCGGGAGCCTCCAGCCTCAGGCAGCC ATCGGGTACTCAGTGGGACTGCCCCAAAAGACCCTCGGCAGCAGGCATGGTCCCCCCAGG TGCCAGGAGAGAGTAAGTACCACAGGCTCCCAGCTCACGGCCAGGCTTCCCTCCAGCTCC TCCTTAGACCAGGCCCCCTGGAAAAGGCTTCTCAAAAGAGGTTCAGTTAGGGGCCGGGAG ATGGGGAGAGGGTCTCGGATCATCGGGGGGGGTGGCCCACCGTCATCACAGAGGCTTTCT AAGGGGAGGCAGGAGGAACACAGTCAGAGGAGGGCGTGAGGGCAGAAGCAGAGGTGGCGG GATGCACAGACGAGGAGGCCCCACGCCGAAGGGTGCAGGCGCCTCTGGAAGCTGGAAAGG GCGGGAGATGGTTTCTCCTGGAGCCTCCAGAGGAACCAGCCCTGTCCACACCTGATTTGA GCCCTGGGAGACCGTGTTGGCCTTGTGACCGCCAGAAATGTGAAACACTAAACCTGCGCT GTTGTGAGTCATGAAATTTGCAGAGACTCCCTGGCAGTGAGGGGCGCTGGCTCAGCTGGG TGGGCCGACAGCTAGGGCTCCTAGCAGGACCCCGCCACTCCCGAGTACGGCCCTCATGTT CAGTCTTCCCGCCTGTGGAACTGGGGTGATCCCATCAAGAGAGTGAAGGAGACGCTGCAG GGGAGCCATCGGCAGGGCCAGCGCAGAGTCAGTGCTCCGTGAAGGGTGGCAGCCGGGAGT GGGAGGCCAGGCACCCACAGCACGTGTGCTTCTGGATGCTTCTGCTCGGCCTCCTGCAAG GGGTTGACCCTCCCTCCTCTGTTTCTAGTTTGCGGCGTGGGCCCCACCCTCGTTTTCCCA AACGCCTCCACCAGGAACGTGGTCTTCCTCAGCCCTGGTTTCGTCACTGCCCTGCGAGCC CTGTCCTTCTGCAGCTGGGTCCGCACGGCCTCCGGCCGCCTGGGCACCCTCCTGTCCTAC GCCACCGAGGACAATGACAACAAGCTGGTGCTGCACGGCCGAGACTCCCTGCTGCCCGGA TCCATCCACTTCGTGATCGGGGACCCGGCCTTCAGGGAGCTGCCCTTGCAGCTGCTGCTG GACGGCCAGTGGCACCACATCTGTGTCATCTGGACGTCCACCCAGGGCAGGTACTGGCTC CACGTGGATCGCAGGCTGGTGGCCACCGGCTCCCGCTTCAGGGAGGGCTATGAGATCCCC CCCGGAGGGTCCCTCGTGCTGGGCCAGGAACAAGACAGCGTGGGGGGCGGATTCGACAGC TCCGAGGCCTTCGTGGGGAGCATGTCTGGCTTGGCTATCTGGGATCGGGCGCTGGTTCCC GGGGAAGTTGCAAACCTTGCCATCGGGAAAGAGTTCCCGACAGGTGCCATCCTGACGCTG GCCAATGCTGCACTAGCAGGCGGATTTGTGCAGGGGGCCAACTGCACCTGCCTGGAACGC TGTCCCTGA OMIM ID 613442