Entrez gene ID | | 3993 |
Official gene symbol | | LLGL2 |
Full name | | lethal giant larvae homolog 2 (Drosophila) |
Aliases | | ,HGL,LGL2, |
Gene summary | | The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q24-q25 |
Gene position | | 73521783 - 73571290 Map Viewer |
Gene orientation | | plus |
Gene size | | 49508 bp |
Gene sequence |
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