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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LLGL2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3993
Official gene symbolLLGL2
Full namelethal giant larvae homolog 2 (Drosophila)
Aliases,HGL,LGL2,
Gene summaryThe lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q24-q25
Gene position73521783 - 73571290  Map Viewer
Gene orientationplus
Gene size49508 bp
Gene sequence