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Gene information for ASIC2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID40
Official gene symbolASIC2
Full nameamiloride-sensitive cation channel 1, neuronal
Aliases,ACCN,ACCN1,ASIC2a,BNC1,BNaC1,MDEG,hBNaC1,
Gene summaryThis gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q12
Gene position32483825 - 31340105  Map Viewer
Gene orientationminus
Gene size1143721 bp
Gene sequence
OMIM ID601784