Entrez gene ID | | 4005 |
Official gene symbol | | LMO2 |
Full name | | LIM domain only 2 (rhombotin-like 1) |
Aliases | | ,RBTN2,RBTNL1,RHOM2,TTG2, |
Gene summary | | LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Location | | Chromosome: 11 Locus: 11p13 |
Gene position | | 33913836 - 33880122 Map Viewer |
Gene orientation | | minus |
Gene size | | 33715 bp |
Gene sequence |
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OMIM ID | | 180385 |