Entrez gene ID | | 4047 |
Official gene symbol | | LSS |
Full name | | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
Aliases | | ,FLJ25486,FLJ35015,FLJ39450,FLJ46393,OSC, |
Gene summary | | The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Location | | Chromosome: 21 Locus: 21q22.3 |
Gene position | | 47648738 - 47608360 Map Viewer |
Gene orientation | | minus |
Gene size | | 40379 bp |
Gene sequence |
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OMIM ID | | 600909 |
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