Entrez gene ID | | 4055 |
Official gene symbol | | LTBR |
Full name | | lymphotoxin beta receptor (TNFR superfamily, member 3) |
Aliases | | ,CD18,D12S370,LT-BETA-R,TNF-R-III,TNFCR,TNFR-RP,TNFR2-RP,TNFRSF3, |
Gene summary | | The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12p13 |
Gene position | | 6493357 - 6500734 Map Viewer |
Gene orientation | | plus |
Gene size | | 7378 bp |
Gene sequence |
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OMIM ID | | 600979 |
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