Entrez gene ID | | 4064 |
Official gene symbol | | CD180 |
Full name | | CD180 molecule |
Aliases | | ,LY64,Ly78,MGC126233,MGC126234,RP105, |
Gene summary | | CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q12 |
Gene position | | 66492617 - 66478103 Map Viewer |
Gene orientation | | minus |
Gene size | | 14515 bp |
Gene sequence |
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OMIM ID | | 602226 |
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