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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CD180 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4064
Official gene symbolCD180
Full nameCD180 molecule
Aliases,LY64,Ly78,MGC126233,MGC126234,RP105,
Gene summaryCD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q12
Gene position66492617 - 66478103  Map Viewer
Gene orientationminus
Gene size14515 bp
Gene sequence
OMIM ID602226