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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MARCKS (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4082
Official gene symbolMARCKS
Full namemyristoylated alanine-rich protein kinase C substrate
Aliases,80K-L,FLJ14368,FLJ90045,MACS,PKCSL,PRKCSL,
Gene summaryThe protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q22.2
Gene position114178527 - 114184652  Map Viewer
Gene orientationplus
Gene size6126 bp
Gene sequence
OMIM ID177061