Entrez gene ID | | 4094 |
Official gene symbol | | MAF |
Full name | | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) |
Aliases | | ,MGC71685,c-MAF, |
Gene summary | | The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16q22-q23 |
Gene position | | 79634622 - 79627745 Map Viewer |
Gene orientation | | minus |
Gene size | | 6878 bp |
Gene sequence |
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OMIM ID | | 177075 |
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