Entrez gene ID | | 4134 |
Official gene symbol | | MAP4 |
Full name | | microtubule-associated protein 4 |
Aliases | | ,DKFZp779A1753,MGC8617, |
Gene summary | | The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3p21 |
Gene position | | 48130769 - 47892180 Map Viewer |
Gene orientation | | minus |
Gene size | | 238590 bp |
Gene sequence |
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OMIM ID | | 157132 |
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