Entrez gene ID | | 4137 |
Official gene symbol | | MAPT |
Full name | | microtubule-associated protein tau |
Aliases | | ,DDPAC,FLJ31424,FTDP-17,MAPTL,MGC138549,MSTD,MTBT1,MTBT2,PPND,TAU, |
Gene summary | | This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q21.1 |
Gene position | | 43971748 - 44105700 Map Viewer |
Gene orientation | | plus |
Gene size | | 133953 bp |
Gene sequence |
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OMIM ID | | 157140 |
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