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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MBD1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4152 Official gene symbol MBD1 Full name methyl-CpG binding domain protein 1 Aliases ,CXXC3,PCM1,RFT, Gene summary DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. Five transcript variants of the MBD1 are generated by alternative splicing resulting in protein isoforms that contain one MBD domain, two to three cysteine-rich (CXXC) domains, and some differences in the COOH terminus. All five transcript variants repress transcription from methylated promoters; in addition, variants with three CXXC domains also repress unmethylated promoter activity. MBD1 and MBD2 map very close to each other on chromosome 18q21. [provided by RefSeq] Location Chromosome: 18   Locus: 18q21 Gene position 47808144 - 47795216  Map Viewer Gene orientation minus Gene size 12929 bp Gene sequence >MBD1:complement(29284318..29297246):Length=12929 AAAGCGCATGCGCCAGCTAGATGGGCAGCGAGGAGAGCCGCAACTGCCAGTCCCTCGAAG GGGTTAGCTGTCGTTGAACGTCAGCACGCAGATGCAACTGGCTCTCGGCAGGGGGGCGCG CGCACCGCTGCGGAGCGCCGGCCCGTAGGCGCGGGAGCCTCCCTATTAAGGGCACGCGAC ATCGAGGCAATAGTGCGCAGGTGCTTAGCCAGAGGCGGAGCCCGAGAGGCAGGCAGCGGA CTTCCGGTTCCGGGAGCAACGAACAGCCGCGGAGGCGACAGCTACCGCTTCAGAGGAGGC GGCCGCGGAGGAGGAGGAAGGGGAGGAGGGCGAGGCGGGAGGTGCAGGAGGGACCCTCGC CATGGGTCCACGGGCCTAGAGTGGCGGAAGATACCGGCCTGGTGCCAAACTGGTGAGACA GCCTTGGGGCTGGACGTGGAGAGCGCTCAGGCGGAGGATGGGAAGGAATTGTGGCTCAGA ACGCTGACGGGGAGGAATGAAGGGCCCTCAGGCCGATAAGGGGGAGGAATGGCGGCGTCG GAATACTGACGAGGAGAAATGGGGGGATTTAGGCTGAGGACGGGAAGGAATGCAGCTCTG AACTCTGACAGGTAGGAGTGTCGGGATCCTGGGACGAGGACGGAGAGGAATGGTGGAGAT CAGAACGCTAAAGGGAGACATCGGGGCATCTGAAGTTGAGAGAGAAATGGGGGTTCAGAA CTCTGAGAGGGAGAAATGAGGGGCCCTCAGGCTGATGACAGGAGAAATAGAGGCTTTGGA ATGCTGAAAGGGAGGAATAGGAGGCCCCATATAGAGGACGAGGAGCAGTAGGGGATCAGA ATGGTGACAGTTAGGGATGGCATGATCCCGGGACAAGAACAGAGAGAATGGAGGAGGGTT CGGAATGCTGAGGGGAGAAATTAGGGTCTCTCTGGATGATAAGGGAGGAATGGAGGATGA GAACAGTAAGGAGGAGAAGTGGGGAACTTTTTGGCTGTAGAGGAAGGTTTGGGAGCTCAG ACTAGGGAGAAATTGTGGGTGAGAACATTGAAGGAGAAGAAAAATAAGGGGGGAGGTCTT GGGCTGAGGAAGGGGAGGCATGGGAGGCTTCCAGTGTGAGGAATGGAAAAGATGAGGGGC TGTTCAGGCTATGGGTTGGAGCAGTTGTGTCTCGCAGAGGAAGTCGAGGTTGTAACACTG AGGTAGCAGGATAAGAGGACATCAGGCAGAGAAGGAATGGAGTGGTTAAAACACTGAAGG AGGGAAATTAGGAACTCCTGGGTCAAGGAAGGGGGGAATGAGAGACTACTGAAGTCAAGT AGTGAGGGCAAGAGAAATGGGGCCCTTTGGGGCTGAGGATGGGGACTATGGGGGTCTTGG GGTGATAAAATAGAGGGATAGAGGCCCTTAGGTCAGTGACAGGGAGGAATGAGGGGGAAG GATGAAAAGTTTCTGGATTGGCAGTGAGGAGAAATGATGGGTTGTCAGTCTGAGGATAGA GAGGAGTAGGGGATTAGGACACTGAGAATAAGAAACAGGGATCCTTGGGTTGAGGAATGA TGATATCCTAGGCCCAGAATAGGAAAGAATGGGGTGAGAATATGAGGGGTTTCTTTTCCA TATATGGGCTGGTTGCCTGTGGCAGGTCCTAGGGCTTGGGCAAGCACTAATGGATACCAG TGATTTGTGTGGCCTGGGGCACAGTGTTGTCCCTTCCTAGAGCCTCAGTTTCCCTCATCC CTTCCACCCCCTTTCAGGCTACTGCTGCTTCCTGTGGCCTCCATGGCTGAGGACTGGCTG GACTGCCCGGCCCTGGGCCCTGGCTGGAAGCGCCGCGAAGTCTTTCGCAAGTCAGGGGCC ACCTGTGGACGCTCAGACACCTATTACCAGAGGTACTGGGTGGGTAGTGGGCAGAGTCAG GAGTGGGGTAGAGCCTGATTCTGGTAAAATCAAATGGTGTGGTTAAATTTATGGATGAAG TTTAAATTATGCACATACAGTTAATCCTTATTAGCGGATTTTATGTTTGAATTTCACCTA CTTAATAAAATTTATTTGTAACTTAAAAGTCACTACTCACAGTGCATTTGTGATTATTCA AGAATACGTACAGAGCAGTGAAAAACTGTCACTCAATGCATGTATTTCTAGCTGAGGCTG AAGGAGCCCTTTTCAGCTTTAATACTGTAAACAGGTGTCCTTTTCGTGGTCTGTTTAGTG TCACATTTTTCTAATTTTTGTACTTTTTGGTGATTTTGCTTTTTAAAATGGTCCCCAAGC ATAGTGCTGAGGTGCTGTTTAGTGTTCTGTGAGAAGACTATGTCGTGCTTTATGGAGAAA ATACAAGGCAGATAAACTTTGCTGGTTATCTGAGTTACAATGCTGTTGGCTGTAAGTTCA ATGTTATGCATCAGAATTATGGTACAACCAGAAAAAGAAGGAAATTTGCCAATATGTGCA CAAAGCTGCTTCAGAAAGTACAGAAAGCATTTATAGTCTTGAAGCTATGTAAGAGATGAG AAAGCAGCTACATTGGTGGGTTCATGAAATGACGATCAATAAAGCATAGTTGACAGCATT GTTGAGGAAAGCCAAAGTCATGTTACCCTGGGTTAGGAAAATATTAAGGTTATATCAGCT AGTGCTGGCTGACTTGCACATTTCAAAAGGCGACATGGCATGAAACATGTTAAACCTGCA TGCAATGCAGGTTCTGCTGATCAGGAGTCTTCCGAAGAATTTTAAAAATACCTGTTAAGT GTTGTACAGGAAAGGGGTTGTGTGGAAGAGTGGTTTTCAATGTCAATGAGATTGGCTTGT TAAACAAGAATATTGGCAAAAAACCTTACATAACACATACGGCCTCCAAGTCCCCTGGTT TGAGTCATTCAAAGACCATGCAAATAATCATTTGTAAAAAAAAATATGTATTAAGTAATG TGTGTTTAAACAGAAACACACACAAAACAAAAGTTCAGATGCTCTCAGGAACCTAACCCT GTATTTCTTCTAGGAGCAATGGTTTTGTATTCAATGTTCATGATAGCTTTGTAGAACGTA ACTACCATAACTAATGAGAGTCAACATAGATGTTTATAAGCATTTACATGTGTTTAAGAA ACATTATTAAGTTTCTATATTCTTTCTGATTTTTTAAATCTAAGTTGCTATCTTTCCAGG TAAATATCAAATTACAAATTACTTTTTGTTTATATTTAGTTATAATTTATTCACATATTT ATGTACTTGTATAAAACTTTCAAAACTTAAAAGTGCAGTTGTCAAGAACTATAAAGAACC TGAGATTTCATTCTTAGGACAAGATAATAGTGAATTTGTCAGAATTTTGTAGATGCTGGT AGGAGGGGTAAGACTCCTGGGTTACAGATCAAAGACAGTTTATTACAACAGTTGCAGGAT CCAGAATACAGTAGTCTCCCCCTTATCTGCAATTTCATTTTCCACAGCTTTAGTTACCTA CAGTCAACCACCATCCAAAAATATTAAATGGAAAATTTTAGAAATAAACAATTCATTAGT TTTGAATTGTGTGCCGTTTTGAGTAGCGTGATGAAATCTCACACCATCCCGCTCAGTCCT GCTCAAGAGGTGAATCATCTCTTTGTCCATATCCGTATCCATATCCATGTTCTAGACACA ACCTGCCTGTTAGTCACACAGTAACCATCTCAGTTATCAGATAGAAAAAACACAGTACAT ATTACATTAGGGTTTGGTACTATCCACGGTTTCAGGCATCCACTGGGGAACTTGGGATGT ATCCCCTGCACGAGAGGGGGAATTACTGTATTACTATTTTTGTGCCAGTTTCTGAATCCC AATTCCTACAGCATGACGTGAAGAGGGTTGTATTATTATAGGAAAAGAACCGTGAGCTTA GAGAATCAGGTTTTTTTTAAATAATATTAAGACAGTAAGTATGCTTTCCCTTTGGAAAAA GTATACTTTCCCTTCCTCCTATGGAAGGAGACCCTATCTCTTATCTTCCAAGGTTGTTTG CTTTACAAACATCCTTGGAAAGATAGTTTATCAAAAAGGACAATCGTTGTCTCTCTTGCA GGGCATACAAAAATGCAAGAAACCCATGGGGGTCCCAAAATCAATTACTTATACTTTAAT TTGTATGTAGTTGCATTTGTTTATATGTTTTTAAAACATATTTGTGTTTTCTTTACTTGA TATATACTTGGTACATAATGCTAACATTTATATGTTATATTTGTGTTATATATATATAAC ACAAATATAATATATTTGTGTTCCTATTTGTGTTTATTTTTACTTACATGAAATAGTTCC AGTATTACTAGTATTATATGTTGTAAATATGTTCATCTGTTTACATTTATATTGTTTCTA ATGTTTCTATATGTGTTGGTATTTATATTAATTTTTTTATGTTTTCAAGGTTAGTTGAGG TGGGGGCTGGGCAGGGCTCACAAGCCAATTCCAGGCTGCCTCCTATATCCTGCCAGCCCT GTCAAAAGGTTGTATGAGTGAAATGGCATTGGCTCCACCTGGGTGCTAACCCATCATGGC CCATCCCTAGCCCCACAGGAGACAGGATCCGAAGCAAAGTTGAGCTGACTCGATACCTGG GCCCTGCGTGTGATCTCACCCTCTTCGACTTCAAACAAGGCATCTTGTGCTATCCAGCCC CCAAGGTACTTCACAACATGAGATACCTAGGTAGGGGTGGATGTGCCACCCAACACCCAA CCACTGACCCATATTCCTCCTTCCCTTACTTTCCAGGCCCATCCCGTGGCGGTTGCCAGC AAGAAGCGAAAGAAGCCTTCAAGGCCAGCCAAGACTCGGAAACGTCAGGTTGGACCCCAG AGTGGTGAGGTCAGGAAGGAGGCCCCGAGGGATGAGACCAAGGCTGACACTGACACAGCC CCAGCTTCATTCCCTGCTCCTGGGTGAGTGTTGGTCTAAGGTGAGCCAGATGGGTGAGGG TTGTGATTGGGGGTGCTCTTGGAGCCCCACACCTGCCTTTCCCATCCCAGGTGCTGTGAG AACTGTGGAATCAGCTTCTCAGGGGATGGCACCCAAAGGCAGCGGCTCAAAACGTTGTGC AAAGACTGTCGAGGTGAGTGGCCTCCAGAGGATGGGGCATCGGGAGATAGGAGCTGGAGC AGGTCCAGTGTCATGCTAGGCTGGGGTTTGAATGTGGATGTCAGGACAGAGGCTACTGGC ATGGTTGGAGGTTGGATATTGGAGATAGCAGGCATAGGTAGAGGTTGAATAGTGGAAGTC AGGGCACAGGCAGTGAGTGAAGTCAGATGTCTGTTGCTTCCTTTCCACTTTTCTTCTTCC CTCTTCCTCCCCACAGCACAGAGAATTGCCTTCAACCGGGAACAGAGAATGTTTAAGGTA AGCACAACCTGCTTCCTCTTCACAACTCTGCAGTGGGAGCAGGATGTGATGGAGCTGGTA GAGTCTGAAGGGATGATGATGGGTCCACAGGATGAAGAGTCATTTTATAGGGTGCTCTCC ATAGGTCAGCAGACACAATAATGGGAATTAATGGGGTAATTAATCCCCATTACCATTAGT GCATCAGTAGACACAGTGATGAAGTGAACAGGGGACCAGTAGACATACTAATGGCCTCAG TGATGGTGACTAACCAGACCTTCTCAGATACGGTGATGAGGCTAATGGGGGACTAAAATT CATGGTGATGCCAGCTGATGTAGGGTCAGTAGACATGGGAGGACCAGTGCTTCTGGAGCA GGCCCGTGATCTCGTCCCTACCATTCCTGGCAGCGTGTGGGCTGTGGGGAGTGTGCAGCC TGCCAGGTAACAGAAGACTGTGGGGCCTGCTCCACCTGCCTCCTGCAGCTGCCCCATGAT GTGGCATCGGGGCTGTTCTGCAAGTGTGAACGGAGACGCTGCCTCCGGATTGTGGAAAGG GTGAGTTGGGCAAGTGGAAAGAGCCCAAGGCTCACCTCGGCCCCTGGCCCCCATGGGCTT GGCCCCATGCTTCATGCCTCTGCTCCCACCTGCCCCCCGCCAACAGAGCCGAGGGTGTGG AGTATGCCGGGGCTGTCAGACCCAAGAGGATTGTGGCCATTGCCCCATCTGCCTTCGCCC TCCCCGCCCTGGTCTCAGGCGCCAGTGGAAATGTGTCCAGCGACGTTGCCTACGGGTGAG TTGGGCTGGAGGGAGCAGAGCTCATTCTGCTGTTAAAATCGTCGCTGCCTCTGCTTCCTT TCAACCTGGCCTTGCCTACCTCATGTCTTTCTTTTCTGCCTAACCCTATGCTCGCCTTTC TGGCCCCGCCTACCTGCCTCTGTCTGCCAGCACCTTGCTCACCGCCTGCGTCGCCGTCAT CAGAGATGTCAGCGACGCACTCCCCTGGCTGTGGCTCCCCCAACTGTGAGTGCCTCACGC CACCCTCTGTCTGCCTGTCCCATGCATGCTTTCTGCACTTAGGGTGTGGGGAGTTTCTGT GTCTGCCTGGTGCCACCAAGCTGAAACCACCCTTTCTGATCTTTCCCAGGGTAAACATGC CCGCCGCAAGGGAGGCTGTGACTCCAAGATGGCTGCCAGGCGGCGCCCCGGAGCCCAGCC ACTGCCTCCACCACCCCCATCACAGTCCCCAGAGCCCACAGAGCCGGTGAGGCCCCAGTG GGTGGAGGGAAGGCACAACCCTGACCTTACCCAGTACCTGCCCTGACCCCACCCCATTTG CCTCTACAGCACCCCAGAGCCCTGGCCCCCTCGCCACCTGCCGAGTTCATCTATTACTGT GTAGACGAGGACGAGCTAGTGAGTGGCCCCACCCTACCTGGATAAGCCTAGAATCTCAGG ACGCTTGGTTAACTTCAAAGAAGCAGATGCTGGAATGAGCCTATTGGGGAACAGCAAGGC ACAATAATGGGTCCTAGGATGGGATGAGTAGATAATGGAGGACTAATACGGGGTCAGCAG GTGCATGAGAGTGCTTCATGTCACATATACCAACACTCTGGTAGCTGATGTGGGGATTGA CAGAGGAGCAGCTAGCATAGTGACTGGGGTTCACCTAGGATGAGCGACAGAGTAGGCACA GTGATGGGAGCTAATAGAGAGTTATCAAAATGTTGCTGGAAATGGGGGTCAGAGACATTT TCTTGGTAGCTAGTGGTGGCCTAGGAAATACAGCAGTGGATACTGTAGTGGAGCAGCCAC AGTCCTAATGGTATCGAGGGCCAGCTGGCACAGTGATAGTGGCCAATGTTGAACTAGCGA ATGCTGAGGAGTGACTAGTGGGGAGTCAGGAGGCTGAGACTAGTATGCAAGTAGCTCCGT CTTATGGGGCTAGAGGAGCACCAGGACCAGCACTGGAATAGGCGTTGAGGATGGCCTCTC CTAGTCCTAGTTGACAGCACCACCCATTCCCCCCACCCCAGCAGCCCTACACGAACCGCC GGCAGAACCGCAAGTGCGGGGCCTGTGCAGCCTGCCTACGGCGGATGGACTGTGGCCGCT GCGACTTCTGCTGCGACAAGCCCAAATTCGGGGGCAGCAACCAGAAGCGCCAGAAGTGTC GTTGGCGCCAATGCCTGCAGTTTGCCATGGTGGGTGGGGCAGGAAGGGTCAGGTGGACGG GATAGGTTGGGCCAGGCGCCCCAGTGCCTGGAAGTGGTGGGCAGGCTTGGTAGGTGGGTG GGTGGGGCAGTAGCTTTGGTTGAGGATTAACAGACATTGTTCTTGGCTTAATGAGTCTAG GTGGCATTGGTGTTGCTAATAGGAGACTAGCAGGCTCAGTGATGAAGGGCTCATATGTAA GCAGATTCCGTGCTGGGACTGATGGGAGATTAGCAGGCATGTGGAGCCGGGCAGGGTGGA TGTGATTGGTCAGGACACCAGGTAGCCATAGCACCCTATCTTTCCCCATAGAAGCGGCTG CTGCCCAGTGTCTGGTCAGAGTCTGAGGATGGGGCAGGATCGCCCCCACCTTACCGTCGT CGAAAGAGGCCCAGCTCTGCCCGACGGCACCATCTTGGCCCTACCTTGAAGCCCACCTTG GCTACACGCACAGCCCAACCAGACCATACCCAGGCTCCAACGAAGCAGGAAGCAGGTGGT GGCTTTGTGCTGCCCCCGCCTGGCACTGACCTTGTGTTTTTACGGGAAGGCGCAAGCAGT CCTGTGCAGGTGCCGGGCCCTGTTGCAGCTTCCACAGAAGCCCTGTTGCAGGTGAGGGCC CCACCCTGTCCTGCCTTCCCAGCCTCACCCAGCTGCATGCCAGGGAGCTGAGACCAAGTC TGCTGCAATCCTCCCTCACGCAGGAGGCCCAGTGCTCTGGCCTGAGTTGGGTTGTGGCCT TACCCCAGGTGAAGCAAGAGAAGGCGGATACCCAGGACGAGTGGACACCAGGCACAGCTG TCCTGACTTCTCCCGTATTGGTGCCTGGCTGCCCTAGCAAGGTGGGGGCAGTGATGGATG TTCTGTTGGTGCCGTAGCGGAGTGGTCTGTAAGCAGAGTGATGATGAGCCATGATGGTTC TCTTGAGCAGAGCAATAGATGTGCTGATTGCGACGTTTCTGCAGAATTACCCCGCCTGTC TAACAGACACCCTACCTCCCACAGGCAACTAGCTTTGCCCGCTTTGCTATCCAGCTAACA GAAAAACGGAGGTCAGTGAGGAATGGGAATGGGAAAGCTTTGTAGGCAGAGAGATGGACT TTCTGTGTTGAAATGTGATGGAAGTAGGATTTGTCAGCACAGTGAGGGGTTGGCTGATAG AGACTTTCCTCAGGTGAACTCTGCCCTTCTAATGGTTGCCTGTTTCCTACTTCTCCCAGG CAGTAGACCCAGGCCTGCCTTCTGTGAAGCAAGAGCCACCTGACCCAGAGGAGGACAAGG AGGAGAACAAGGATGATTCTGCCTCCAAATTGGCCCCAGAGGAAGAGGCAGGAGGGGCTG GCACACCCGTGGTCAGTGCTGGGGATGCCCCACCCTGCCCTGACCCTGCTGTAGCCCCAA CAACCACATTGACCTATGGTGTTAATTCTTCTCTAGATCACGGAGATTTTCAGCCTGGGT GGAACCCGCTTCCGAGATACAGCAGTCTGGTTGCCAAGGTGTGCCCCACACAGTGAGGGG TGGGGAAGGAGTGGGTGTTGGCCAGATGTGGGCCCTGAGTTTTGAAAGTATAGCCGGCAG TTTGGCATGGTGTGGTGGGAGGTAAAGGCCCATACCCACTATGCTGGTCACAATTAATGA GGGGCGTGTGTGTAGGACCCTAGAGATTTCTCCTGAGATCCAGCCCAATAGCATTCCAGG TTAGGACTCTCCTTTGGGGGTAGGGGAAAGACTTGGTACTCTATCATGAGATTTGAAAGA AAAAGATAGGGAGTCTGGTCCCTATTTTCCTAAGGAATTTCTATAGGGGTCAGCTTTAAT ATATAAATTCTTATTCAGAGAATAATCATTTGGGTCTTGAAGGCCTTTAGAGTCTCCAGG AGACCTCTGGGTGGGCTGTTGCCTGACATTGAGCAATGTGTACCAGAGAAATGGTGCTGG GCTTGCCTGGGCAGTGGTATGGGCAGGAGATCTGGGTTCCGAGCTGGCTTTGTGAGCTGG GTTCACACGTAGTTGTGTGATCTCTGGTTGCCCTGCACTTCCTGGAGCGGCCTCTGTGGA AGGGCTTGGGCTGGATCTCTTGAGCCTTTCCTGAGCCTATTGAGGTTATTAACTTCAGAT GCCTTGCAGAACTGTCCCTGTAGTCCTGGCATAGAACAAAGGGTAGATGCCTGTAAGGAC TAGGGTGGTTGGGAGGACAGAGGAGTGCTGGCTCCTGCAGAATATTGACAGACCCTGCAT AGAGCCCCAGACACTGGCGATGTAAACTATTGGCCTAAGCACTTGGATTCCTTTGCTCCT ACAAACCAGCCCACCAGGCTAGAAACCCTTTCATCTATACTTGGCCAATTACAGAAGTAT TGATTGAGTTCCTGTTGGGTGCACAGCATTGAGGACAATGAGCCCTGCAAAGCTTACCCT TCAGGAGACACAGGATACCTACCTTCAGGGAGCTTATAATCTGACTATGTACAAGCTGTC TATAATGGTAGTTTTTAGAAGATATAAAAAAAGATAAAGGATAATTAAGGGGAAGTGGAT GGAGGACACAGAATAGTAGGAAATGGTTTTGTAATGCTCCATTGCGCACATAGCAAACCT CATTCAACATACAGACCTGCTCCCTTTTCCCTAGGTCCAAAGACCTTAAAAAACCTGGAG CTAGAAAGCAGTAGACTGGAGGCTTCTACAGACTGTAGGATTCAAGGTGATATTTGCAGA CTGGCTTTATGAGAGACAACACTGATCTACTAGGGGCTGGACCCTAGATTGGTTGCCAGG GCTTGTGTGTGAATCAACCCTAGGAGGAAAAACCTACTACCAAACCAGAAGAGCAGGCCT AAGAGTACTTTGAGCTTCTAGAAGAAGTAAGCGGGAAAGGAAGAGAAAGAGTAGAAAGTT GGTGCATCTTCTCCTCCCCAAGAGCCTGAGTATAAGAAGTTGGATTTTAAGGGTGGGGGA GCTGGGTTGGAGAAAGGTAATATAATTAAAGCCACCACAAAACAACCTAAACAAGCCATG TTCATGAGTAATTGTAAGTGGCTTCTGGATGAGACCTGGCAGTGTCTCTACATACTTCCT CAGGGAGATAGCAATTGAAAATGTAATTGAATAAATAAGGAAAGGAACTGCTATTTGGTG TGTTCCTCTGTGGACCCAGTTTATTTAATCCTTAAAATAATATTTTTGGGAAGACATTGA TTTTGTCCATTTATGTGGATGGGAAAACTGAGACTCATTAATTTGTCCAATGTCGAACAG CTGGTGTTAGTAGAGCCTAGACTCAAACCCAGCTTTTAAAGCCCTTGTTCTTTACTCCAC TAAACTGTAACCTGTAATCCTGTATGCACTAACAGGAGTTTTCGGTGACCTTGAAAACAC AGATTACTATAATTACTATAATAAATCCCTTACATTCCTGTCTCTAGCATGGTTTAGGGA GTGCCAAGGCTCAATGTAGATGGGGTCACCTTGTCAGAGCATCTGTTCATACAGAAACTG GGTTTCCTGCAGACCCCAGGTGCTGCATAGGATTCCTCAAACCCTACAGGATATATCTCC CCACTGGCTGCTGTCCATTTTGCTTGTTACCCTGACTCCCCCTCTTCAGCCAGAGCAGTC TTTGTAACTAAAGCTGCCAGCCTGGCTCATCTTTCCTGACAACGTGCATCTCCTGCCCTG TGATCACCTTTGTGCTTGGCTCCTGCCCTCAGCCTGAATGTGTTCTAGGAGGCTGAATTC CTGCTTCGAGTCCTGCCCAAGAGCCAGTCTTGGCTCAGCCCTACCTCACTCTCTCCCAAT TCTTCATTCATAAAGTGCCAAAAAGATTAGACCTGTAATTTGTTAGCCAGCTTTACAGGG CCAGGACTGAGTGAGTGCCTCCTTAAACTTTGTATCCTGTGTGCCTCCCTTGCCTTACCC TAGTCCCAGCCCTGCAGCTTTAAGTAATTCAGACATGGATTAGCCATTTCCCAGTTCTGT CTCATACAGTCCAGCCTCTGCCACCTTCCCCACCCCTTCCTTTATTCCATCCTAACTAGT TCAGCCCTAGTCAAGACTGGATAGACTGATACTGCTTTGTTTCCCCCAGGAACCAACCAC CCAACCCCAGTATTCTGGTAATTTTGACAATGATCTATATGAAATTTATTTGATTGACAT TTAGACTCATGAGTTAAGCTTCTGCTGACCATTTATGTTAGGGTACAATCAGAGGAGCAG AACCACTAAGATAAAGATTATGTATATATGTATTTTAAGGGATTTATTATAGGGATCTGA CCGCATGCCATTGTGGGAGCTGGTTAAACAGTCTCTGTAAGGCTGTTGTCTTTGCATCTA ATGCTGGAGCTTGAAGTCTGCAGGGCAGGCACTCGGGAAGGGAAGATGGATGTAAAGTGT GGGAGACCGAGGACACAGTGGAGCCCACGAGCACGAGCTGGAACCCACGAGGATGGCCTG GAACCCATGTCAGTCTCTCACCACCTCCAGCTTCGATGATGTGGGTGTCCTGCAGAAGAA GCTGGTGCCCTTCCTCACAGAGTTAAATATGCATCTGGCCCAGGAATTAGAGAAGCTGAA AGGATGATCCTGGGGAAGGTGGAGCAGCTGCAGGCCTGGCTGCAGGCCTGACTACTGCCC ACACCAACGAGGTGATCTAGCAGATACATGGCAACGTGTGAACTGCAACAACGCCTGGTG CCCCAGCACCAACCTTCCAAGTGTAAAAACAATGTGCTGCTGCTTCACTTCCGCCCTCCG GTTATCAAGCAAAATGTCTCTTGTGGCCCATCTTACTGGAAGAGAGTTCCGGGAAACATA GCCTCACCAAGGTGACACATTACAAAGCCACCCTACCATGAATCCGCTCCCAAGGGTCTC ACTGCTCACCTGAGGATAACTCAATATAACTATGTGGCTGAAAATGCAAAGCTGAAGACC ATGGATTTCATGGTGATTCCAGCAAGTACAGAGATTCTATGAAGCCCACCCAGAAAAAAC TTGCTGGTCCTGGCTATTTTTGTGTCATTTATTCAAGTATTGAGAACCTGGCCTGTGGTA GGCACTGTACTTAATACTAGGATACAGAAATGCAAAAGATACGGCCCATGCAATTTTATT AAATGCATCAATATGTATTACAAATGGTGAATGGATTTCCAACTTTATCATGGAATTTAA TGCTGAATATATAGAATTCAGAAAATTGTTGGGAGGACAGCCCTTTTGTGAACCTTGTTT GGGGCACAGTAGGAATTGGAAATAATTTAGTTTCTATCTCTAAGCTGTTCTATTTTAAAA TTATTTTTAAATTTTTATTGTCCCACTTA OMIM ID 156535