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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MDM4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4194
Official gene symbolMDM4
Full nameMdm4 p53 binding protein homolog (mouse)
Aliases,DKFZp781B1423,HDMX,MDMX,MGC132766,MRP1,
Gene summaryThe human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Two transcript variants, one protein-coding and the other likely not to be protein-coding, have been found for this gene. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q32
Gene position204485511 - 204527248  Map Viewer
Gene orientationplus
Gene size41738 bp
Gene sequence
OMIM ID602704