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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MEN1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4221 Official gene symbol MEN1 Full name multiple endocrine neoplasia I Aliases ,MEAI,SCG2, Gene summary This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq] Location Chromosome: 11   Locus: 11q13 Gene position 64578766 - 64570986  Map Viewer Gene orientation minus Gene size 7781 bp Gene sequence >MEN1:complement(9876781..9884561):Length=7781 TATATTTATGTATATGCACATACACACAAAATTAGGCGGGAGTGGTGGCGCACGCCTGTG ATCACAGCTACTCGGGAGGCTGAGGCACGAGAATCGCTTGAGCCCGTGAAGTCGAGGCTG CAGTGAGCCCAGATCGAGCCACTGCATTCCAGCCTGGGCGAAAGAGAAAGACCGTGTCTC AAAACAAACAAACAAAAGCTACTCTTAGCACGTGTTAGAGTATCTCGCGGGCGGAAGTGG GAAACGAGTGCTGCACACAGAGTAGGCATCTTTATATGTTAACAGACACTGATACCCAGC TAAAGCGGCTGAACACATTTACTCTCTGGCAGTGTTTAAAAGTATCTGTTTTTCTCATAT TGTTTTATTTTAATTTTTTCTGGATCAAGCAACCTGATCTTTTTCCTCATAACTTGCCGA CCGACCCGTGACAGCAAAACCGGCAGAAGCTCGGCGACCTCCCACCCCGAGTCTGCAGGT AGTGCCCCCGGACTACATTTTCCAGAAGGCACTGCGGGCACGCTTCCTGCCTGGTCGGCC TGAAGGGAAGGGCCAATCCCTGAGTATCTCGGGAAGGAGGTGTCCGGAGCCGCGGACCTA GAGATCCCAGAAGCCACAGCGCAGCGGCCCGGCCCGCCACTATTTCCAGGCTCAGCGGGG CAGGGGTGGGCCCAGACTCCACTTCCCGGCGGGTAGTGCGACCCTAGGGGCGGGACTTCA TGTCCCAGCAGGCTCCGGGCGGCGTGCGCCGCGGTGCCTAGTGTGGGATGTAAGCGCGGA GGTGGGCGAGGGGGACCGAGGCCAGGACTCTCCTTGGGGTTTGGGGGCTTGACCTGGGTG CGCTTTCTGGACAGACTTTACAGCCCCGGGGGCACAGTCGTAGAGAGGGGGCGGGGCGGC CATTGGGGCTCCTCATTGGGGTGCTTGGGGCGCACCCCATCGGGTACCGGGCGTCCCGGA ATTGTGGGGGACAAAAAGGCTCTGCAGTCTCGGCTGAGGGGTCTCACCGACAAAAGAGGG GAAGCCGGTGAGCAGAGGCTGAAGAGGGTGGGGAAGCAGGGGAGCTGTGCGTGTGTCGGG GCGGGTGGAACCTTAGCGGACCCTGGGAGGAGGCTCCCCGGCCGAACCTGCCCGACCCTC CCTCCCCCGGCTTGCCTTGCAGGCCGCCGCCCACCGCCCGCCGCCATGGGGCTGAAGGCC GCCCAGAAGACGCTGTTCCCGCTGCGCTCCATCGACGACGTGGTGCGCCTGTTTGCTGCC GAGCTGGGCCGAGAGGAGCCGGACCTGGTGCTCCTTTCCTTGGTGCTGGGCTTCGTGGAG CATTTTCTGGCTGTCAACCGCGTCATCCCTACCAACGTTCCCGAGCTCACCTTCCAGCCC AGCCCCGCCCCCGACCCGCCTGGCGGCCTCACCTACTTTCCCGTGGCCGACCTGTCTATC ATCGCCGCCCTCTATGCCCGCTTCACCGCCCAGATCCGAGGCGCCGTCGACCTGTCCCTC TATCCTCGAGAAGGGGGTGTCTCCAGCCGTGAGCTGGTGAAGAAGGTCTCCGATGTCATA TGGAACAGCCTCAGCCGCTCCTACTTCAAGGATCGGGCCCACATCCAGTCCCTCTTCAGC TTCATCACAGGTTGGAGCCCAGTAGGTGGGAATCTTATCCATGACCCACTTCTTCAAAAC CCTCCATGGTTTACAGAACCCTTTTAAGAACTGTAAGCCTTGTGAGGTTCGGCAGGTGTT ATTTTCCTCTTTGCAGTTGGGAAACTGAAGCCCAGAGAGGGGAAATGATATGCCAAAGTC ACACACGGCATGGCAGGGCTGGAAGTGAAGCCTGATCACTTGGCTCCAAATCATCAACCT CACCTCTGCCCCCTCAGCACCCCCACCCTTGCCACTGAACAGCTACAGGAGTTCTAAGCA TGAGACACAGAGGGCGGCAGCAGATTTAGGGGGCAAGAAGATGAAATTGGGCTGCATTTG AGGCAGTTAAACAAAATAATGGCTATGAAGATTTTTTTTTTTTTTTTTTTTGAGACAGGG TCTCACTCTGTCCCCCAGGCTGGAGTGCAGTGGTGTGATCATGGCTCACTGCAGCCTCAG TCTCCCTGGGCTCAGAGATCCTCCAACCTCAGCCTCCTGAGTAGCTGAGAGTACAGGCAT GCACCGTGGTGCTGGTTAATTTTTTGTATTTTTTTTGTAGAGATGGTGTCTCACTATGTG GCCCAGACTGGTCTTGAACTCTTGGGCTCAAGTGATCTGCCCGCCTCAGTCTCCCAAATG CTGGGATTACAGGTGTGAGCCACCGCAACTGGTGGCCTATGAAAATTTTTTTTTTTTTTT CAGACGGCGTCTCACTCTGTCGCCCAGGCTGGAGTGCAGTGGTGCAATCTCGGCTCACTG CAAGCTCTGCCTCCTGCTTTCATGCCATTCTCCTGCCTCCTGCCTCAGCCTCCTGAGTAG CTGGGACTACAGGAGCCTGCCACCATGCCTGGCTAATTTTTTTTTGGATTTTTAGTAGAG ACGAGGTTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCGC CTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCTGGTCAAAAATGTT TGAGACAGAGAAGGGGCTTGACCTCAAAAGGCTTAAGAGTCAGGGCTTGCAAAGAGCTTT GCACCAAGCCCGGTTGACTGGCAATCCCATCCTGGTGTGCCATATTGAGAAGGAATCAGA GGCTGCTTCTCAGCTTAGCAGGAAAAGAGTGCAGAGATAAATGAGGGTTATTTGTTGGTG GGTGTATAGCCAGAGAGTGTTGGCCAGCGTCCTGTTTTTGCCATTCCTGTTTTAACCTAG TAAGTGCAGTAAAATGGAATCCCTAAATCCATAGAATATATAATAGAGTTGCAGAGAAAG ACGAGGTAGGGCCAAAGGCTGGGTCAGCTACAGGATATCCAGAAAGGTATCTTGTTGGAC ATAGAGGGTGTAAACAGGGAGAGAGTCTTTGAACACGTGGGAGGGAAGGGATGGAGGGAT AGTGGGCAGGAGAATCTGAGGTTGGGTCACAGGCTTGGAAAGGGAGTGGGAGGGAGTGTG GCCCATCACTACCTGGCCCCCTTTCCCCATGTTAAAGCACAGAGGACCCTCTTTCATTAC CTCCCCCTTCCACAGGCACCAAATTGGACAGCTCCGGTGTGGCCTTTGCTGTGGTTGGGG CCTGCCAGGCCCTGGGTCTCCGGGATGTCCACCTCGCCCTGTCTGAGGATCATGCCTGGG TAGTGTTTGGGCCCAATGGGGAGCAGACAGCTGAGGTCACCTGGCACGGCAAGGGCAACG AGGACCGCAGGGGCCAGACAGTCAATGCCGGTGTGGCTGAGCGGGTATTGTTCCCTCCCC CCAGCCTTGTCCCCTTCATACTGTAGTAGCCCAAGCCACCCAAGGGACTCCATTTTCTTG GGCCACACCCCTTTCTTCCCATCACCACCCACATAGGAAGGGAAGACAGAAGAGCCCCTT TTCCTGGCTGTCATTCCCTGAAGCAGGCACAGGGTGGGCCATCATGAGACATAATGATCT CATCCCCCCCTAAGAGCTGGCTGTACCTGAAAGGATCATACATGCGCTGTGACCGCAAGA TGGAGGTGGCGTTCATGGTGTGTGCCATCAACCCTTCCATTGACCTGCACACCGACTCGC TGGAGCTTCTGCAGCTGCAGCAGGTGAGGGCTGAGCCAATGGGGCAGGACTGGGCTAGGC CAGACTTGACTTGCTGTGGGACCCTGGGCAGGGGCACTTTCCCTTCCTGAGCTTCAGCTT CCCCTCCTGGAAAAATGGGTTAGTAATTCCTGGCCTGGCCTTTCCCAGGGCTCTTGGGAG AGTAGAATTGAGATGTGAAATTGCTTTGACTCCATTAAAGGGCTGGTCCCAGAATTTTGG CCCTTCCACATGGTGGGTGGTCCCTGTTGGTTCTGACCCCCACCTCTGCCCGATAGGCTA AGGACCCGTTCTCCTCCCTGTTCCGTGGCTCATAACTCTCTCCTTCGGCTCCTAGAAGCT GCTCTGGCTGCTCTATGACCTGGGACATCTGGAAAGGTCAGTAGAGGGAAGTGGCCAGGC TGCGCCTGGTGAGGCCGGGGGGCTGGGTGGCAGCCTGAATTATGATCCTTTCCTAGGTAC CCCATGGCCTTAGGGAACCTGGCAGATCTAGAGGAGCTGGAGCCCACCCCTGGCCGGCCA GACCCACTCACCCTCTACCACAAGGTGGGGGCATCTAAGGAGGGTGCAGAAGGGAGACCC TAACAGTGGCTGAGGCAGGGGCCCTCATCTGGGCAGATGAGAAGAGAACTTTGTGTGTTG GGGGGTATCGCCCATCCAGTCTCACTTTGTGTCAACTGTGTGCAGAATCAGTTCAGTCAG GGCTGTCTGAGGGGTGTCCAGGGTTCCCCAGCCTGGGAGTGGCAGGGGCTGCATTTGTCC CCTCAGCCCTGCCTTTTCTGCCACTGCTTACTGTCCTTCCTGGAGTATAACAGAGGTCAA ATGTGGCAGGAGCACTGATGAAGAGGGGGTGTTCACTTGGTGGGTGTAGGTGGGGAGGAG GGCCATTGGGCTGGGCTTGAAAGTCTTTGGTGATGTGTAGAAGAGTGTCTGAGAAAGAGA AGGGCCCTGAGCTCGGAGGGCAGGCCCCACCCCTGCAGTCTGCCCCAGGCCTCAGCCAGC AGTCCTGTAGACCCAGGGAGGAGACCAGGTAGAAGGGCTGGCAGCGAGTGGAGGTGGGAG TGGAGATGGAGAGGACTCCCTGGGATCTTCCTGTGGCCCCTTCTGGGTGTGCCCTGGTGG GGCATTTGTGCCAGCAGGGCAGCTGGGGCTGCCTCCCTGAGGATCCTCTGCCTCACCTCC ATCCAGGGCATTGCCTCAGCCAAGACCTACTATCGGGATGAACACATCTACCCCTACATG TACCTGGCTGGCTACCACTGTCGCAACCGCAATGTGCGGGAAGCCCTGCAGGCCTGGGCG GACACGGCCACTGTCATCCAGGAGTGAGGATCCCCCTACTAGGGCCTGCAGCCTGTCCTT TCTTCCCCTCCATCAGTTTCCAACCACCCTCGTCCAGGACTGAGGCCTGGCTCCCACGCC CCATCCCCTTTCCATCCAGTCCCTAGGCAGCAAGGCCACCATTACCCAGGAGGTAGGGAC CCTGATTAAGGTGTCACATCTTTCCCTCCCTCCCCTCTCCTCCTAATTTTTTTTTTCTCA GAACAGTCTCAAATCTCCAATGTTTAACCACCATCATCCAGCAGTGGGACTTCCACCCTC GGCCCCATGCCCCCCTCCTCATTCTTGCTTTCTTCCTCTGGGCTGACCCAGACAGCATCA TTTTGCAGTGAGGACCCCACCTACTCCCCCAGCCCCTGGGGGCTCCATCCCCCGCCAGGT CCCTGGGGCTACCCCCGATGGTGAGACCCCTTCAGACCCTACAGAGACCCCACTGCTCTC ACAGCTACAACTACTGCCGGGAAGACGAGGAGATCTACAAGGAGTTCTTTGAAGTAGCCA ATGATGTCATCCCCAACCTGCTGAAGGAGGCAGCCAGCTTGCTGGAGGCGGGCGAGGAGC GGCCGGGGGAGCAAAGCCAGGTGAAAGGCTGGAGCTCCAGCCTGTGTCCAGCCTCCCACC TGGACAGGGCTCCCTTCCACAGGCCATGGGGGCTGCATGTACGGGATTAGGGATGGCAGG AGGAAGGTGGCCCTGAGCAGACAGCTATGTTCCCTTTTGCTATAACTGAGGTCCTGGGCC CACGTTGGACGGGACTGAAGGTATTTTAGAGGTTTCTACCCTGTGCCTTCAGTTTCATGG CCAGACTCCCTCCCTCAGCTGAGGGGTGGAGGTAGGGATGGTACGTCCTGGCTATGGATT GGCTTTATAAAAGGAAAGAGGTTCTAAGAATGTTCCCAACCTATGCTTACCTTTTCTGGA GCCAGGGGTCTTTGCCTAGGTGGGGGGCCTGGCCTGTGCCCTCTGCTAAGGGGTGAGTAA GAGACTGATCTGTGCCCTCCCTTCCCCCTCGTCCAGGGCACCCAGAGCCAAGGTTCCGCC CTCCAGGACCCTGAGTGCTTCGCCCACCTGCTGCGATTCTACGACGGCATCTGCAAATGG GAGGAGGGCAGTCCCACGCCTGTGCTGCATGTGGGCTGGGCCACCTTTCTTGTGCAGTCC CTAGGCCGTTTTGAGGGACAGGTGAGGGACAGCTGCACAGAGGTCTGGGCACTACAGGTG GTGACAGCAGCCACGGGCTTGTCAGACTTTTCTGGCCCAGGGGCAGCATCTGCCCATCCC CTTGGGTGCCGATGGGACTGAGACCCCCTGGGTGGGATGGGATGGCCAGAGCAGGGTCCT GGAGTTCCAGCCACTGGCCGGCAACCTTGCTCTCACCTTGCTCTCCCCACTGGCCCAGGT GCGGCAGAAGGTGCGCATAGTGAGCCGAGAGGCCGAGGCGGCCGAGGCCGAGGAGCCGTG GGGCGAGGAAGCCCGGGAAGGCCGGCGGCGGGGCCCACGGCGGGAGTCCAAGCCAGAGGA GCCCCCGCCGCCCAAGAAGCCAGCACTGGACAAGGGCCTGGGCACCGGCCAGGGTGCAGT GTCAGGACCCCCCCGGAAGCCTCCTGGGACTGTCGCTGGCACAGCCCGAGGCCCTGAAGG TGGCAGCACGGCTCAGGTGCCAGCACCCACAGCATCACCACCGCCGGAGGGTCCAGTGCT CACTTTCCAGAGTGAGAAGATGAAGGGCATGAAGGAGCTGCTGGTGGCCACCAAGATCAA CTCGAGCGCCATCAAGCTGCAACTCACGGCACAGTCGCAAGTGCAGATGAAGAAGCAGAA AGTGTCCACCCCTAGTGACTACACTCTGTCTTTCCTCAAGCGGCAGCGCAAAGGCCTCTG AACTACTGGGGACTTCGGACCGCTTGTGGGGACCCAGGCTCCGCCCTTAGTCCCCCAACT CTGAGCCCATGTTCTGCCCCCAGCCCAAAGGGGACAGGCCTCACCTCTACCCAAACCCTA GGTTCCCGGTCCCGAGTACAGTCTGTATCAAACCCACGATTTTCTCCAGCTCAGAACCCA GGGCTCTGCCCCAGTCGTTAGAATATAGGTCTCTTCTCCCAGAATCCCAGCCGGCCAATG GAAACCTCACGCTGGGTCCTAATTACCAGTCTTTAAAGGCCCAGCCCCTAGAAACCCAAG CTCCTCCTCGGAACCGCTCACCTAGAGCCAGACCAACGTTACTCAGGGCTCCTCCCAGCT TGTAGGAGCTGAGGTTTCACCCTTAACCCAAGGAGCACAGGTCCCACCTCCAGCCCGGGA GCCTAGGACCACTCAGCCCCTAGGAGTATATTTCCGCACTTCAGAATTCCATATCTTGCG AATCCAAGCTCCCTGCCCCAAATAACTTCAGTCCTGCTCCAGAATTTGGAAATCCTAGTT TCCTCTCCTTCGTATCCCGAGTCTGGGACACAAAACTCCGCCCCCAGCCTATGAGCATCC TGAGCCCCGCCCTCTTCCTGACGAAACTGGCCCCGGATCAGAGCAGGACCTCCCTTCCGA CCCTCTGGGAACCTCCCAGAGGTCCAGCCCATCTCGGAGCATCCCGGAGGAAATCTGCAG AGGGTTAGGAGTGGGTGACAAGAGCCTGATCTCTTCCTGTTTTGTACATAGATTTATTTT TCAGTTCCAAGAAAGATGAATACATTTTGTTAAAAAAAATA OMIM ID 131100