Entrez gene ID | | 4301 |
Official gene symbol | | MLLT4 |
Full name | | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
Aliases | | ,AF-6,AF6,AFADIN,FLJ34371,RP3-431P23.3, |
Gene summary | | AF6 is a Ras (see HRAS; MIM 190020) target that regulates cell-cell adhesions downstream of Ras activation. It is fused with MLL (MIM 159555) in leukemias caused by t(6;11) translocations (Taya et al., 1998 [PubMed 9722616]).[supplied by OMIM] |
Location | | Chromosome: 6 Locus: 6q27 |
Gene position | | 168227671 - 168365793 Map Viewer |
Gene orientation | | plus |
Gene size | | 138123 bp |
Gene sequence |
| |
OMIM ID | | 159559 |