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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MMP1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4312 Official gene symbol MMP1 Full name matrix metallopeptidase 1 (interstitial collagenase) Aliases ,CLG,CLGN, Gene summary Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq] Location Chromosome: 11   Locus: 11q22.3 Gene position 102668966 - 102660641  Map Viewer Gene orientation minus Gene size 8326 bp Gene sequence >MMP1:complement(6223057..6231382):Length=8326 AGCATGAGTCAGACAGCCTCTGGCTTTCTGGAAGGGCAAGGACTCTATATATACAGAGGG AGCTTCCTAGCTGGGATATTGGAGCAGCAAGAGGCTGGGAAGCCATCACTTACCTTGCAC TGAGAAAGAAGACAAAGGCCAGTATGCACAGCTTTCCTCCACTGCTGCTGCTGCTGTTCT GGGGTGTGGTGTCTCACAGCTTCCCAGCGACTCTAGAAACACAAGAGCAAGATGTGGACT TAGTCCAGGTAAATGCTGCATTGCATGTGACAATAATGTAAATTTTTAGTTTGTATTTTT CTGCAGTAATGTAATAGAGTTTTTTAAGGATAGGTTTCTTATAAAGAGATTTTTTTTTTT TTTGCTAGAAACAGCACCCTCCACCCAAAATGTATCTAGCCATGCATACGCTCTCTTTTT CCAGTTGGAGGTGAGAGTGAACTAAAGGAACAACATCCAAACTTGTCTCCACAAATTGTA GACTTGTAACAGTATGCAAATCTTGCTCTACAAAAATTGCTCTACTATGAAGTTCTTACT TCACAATAACTAATAGTAGGGACATTTCTACTCTGAAATTTCATTTCTCACCAAAAATAA GGATAAAAGCAACTGCGAAATCTAAACACAAGGTTTAAAAGCAGTTCTCTGTTTTGGCTA AAACTTAATGCCATCAATTTTTAGAATAATGAGAAAGATTTCCCATGCAGTGTTTCGATA ATTTTCTTTTGTCAGAAATACCTGGAAAAATACTACAACCTGAAGAATGATGGGAGGCAA GTTGAAAAGCGGAGAAATAGTGGCCCAGTGGTTGAAAAATTGAAGCAAATGCAGGAATTC TTTGGGCTGAAAGTGACTGGGAAACCAGATGCTGAAACCCTGAAGGTGATGAAGCAGCCC AGATGTGGAGTGCCTGATGTGGCTCAGTTTGTCCTCACTGAGGGGAACCCTCGCTGGGAG CAAACACATCTGACCTACAGGTAGGCAGACTGAGGGCCAGAGTGAGAGAGCTATTTCCCA TGACAGTGGTAAGAAGTCATGTCCAATGTGTCTCTATTTTGTTTCATTCTAAGGATTGAA AATTACACGCCAGATTTGCCAAGAGCAGATGTGGACCATGCCATTGAGAAAGCCTTCCAA CTCTGGAGTAATGTCACACCTCTGACATTCACCAAGGTCTCTGAGGGTCAAGCAGACATC ATGATATCTTTTGTCAGGGGAGGTAAGTTCTTCTTATAGCACCTTAACCTCACCTTGCCC CTAGATCTCGTAGCTTTGCAACTGGAATTGATTGTTTAAGATGAATGTTGATTTTATGGG CTCGAAGAGGGAAACTGCATCACAGTTGATGGAAGTCTGTTGGCCTCTTAACAAAGCTAA TGCTTGCCCTTCTGGCTTAGCTTACATAAGAACCACAAGGAATCTTTGTTGAATTGTTTC TTTCAGATCATCGGGACAACTCTCCTTTTGATGGACCTGGAGGAAATCTTGCTCATGCTT TTCAACCAGGCCCAGGTATTGGAGGGGATGCTCATTTTGATGAAGATGAAAGGTGGACCA ACAATTTCAGAGGTAAGCCAATCAAATTTGCCTCTCTCAATTCTCCCACCCCTTCATGTT TCATTGTAATATTGGTTGATTTAGTTGAAAGAATGCATTCATAGAAGTATATATTTTTCT ATTACCACTCAGAAAATTAGTGATACACTTAGAAAAGTGAAAGAGCGGTCTTTTCTGCTA GCTAACAACATCTTAGCAGTGACAACTAGGCCACTCTAAAATTTTTATTAAGAAAATTGT TGAAAACTTTGATGTTTTAATTGTGGGCATCAACATTGAAACTTTTTCATTAGAAGAAAA CAGTGAAATTTAACAGCGGTCATAAACTTATGTGGAAATTAAAGAAAAGGAAGGCTTTTT GTGTTTTCCAAAATTTCCAGCAGTCAACATTTATCAGTTTTGTAAATAAGAAAAATATTA AATATTAGGCTGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGC AGGCAGATCACAACGTCAGGAGTTTGACACCAGCCTGACCAATATGGTGAAACCCTGTCT CTTCTAAAAATATAAAAATTAGACAGGCATGGTGGCACACGTCTGTAATCTCAGCTACTC AGGAGGCTGAGGCAGGAGAACCGCCTGAACCCAGGAGGCAGAGGTTGCAGTGAGCCAAGA TCATGCCACTGCCCTCCAGCCTGGGTGACAGAGCAAGACTCCGTCTCAAGAAAGAAAAAA AGAAAAAGAAAAATATTAAATGTTAATAGAACATTTTGCTTCTGTGTGAAATAGTACGTG TCATTTAATCATTGATAATATTGATTAATCTGTGGTGCGCTTTCAGTCAGCTGAGTTTGT CTTTTAATTGTATCAATGTAATCATAGAGTTTAGGTTTCAACATGTCTCTTCGTTATTAA TAAATGCATGCCTTCTGCCTTCGGAAAAAAGATATACATGCATATATTTCAAAAGTCACT GATAAAATAGTAACATGAGTCCTTGTAGTTGTAAATTATTTATTAGTTAAATGCCTCAAA ACTGAATACCTTTCAAATAATTACAAATTGATTTATTGGCCTTTTTAGAGTACAACTTAC ATCGTGTTGCAGCTCATGAACTCGGCCATTCTCTTGGACTCTCCCATTCTACTGATATCG GGGCTTTGATGTACCCTAGCTACACCTTCAGTGGTGATGTTCAGCTAGCTCAGGATGACA TTGATGGCATCCAAGCCATATATGGTGAGTATGGGGAAAAACATTACGGACAAGGGCCTG GTGGTCTTTATATGTATTTCAAATAAAACAGCCATTAGCGATATCCTTGAAGAAGCTGTC TTCATTGTTTATGTAGTTTTCTAATACTAGGCAAAACTAACTCTAGGTATTTTATTTTCC TTAGGACGTTCCCAAAATCCTGTCCAGCCCATCGGCCCACAAACCCCAAAAGCGTGTGAC AGTAAGCTAACCTTTGATGCTATAACTACGATTCGGGGAGAAGTGATGTTCTTTAAAGAC AGGTAAGATGTCAGTTCTTCTTTGTGATCTGCATTTGTAATAATAACAACATTCACCACT ATGATTAACTATTATGCTTCACATGTTACTTATTTCATGCTGATTTACATCTATAATCAC ATGGTAGCAACCACATGCATTTGTGCAACATAATGTACTTGTAACAACTTTGTTTTTCTA CATGTATTAGGTCAACTGATTCTCAGAAAATATAGTTGATTTTGAAAATCAGTATGTATG ATCTTTTTTTACAGATTAGCAAAGTAAGTCAGAGAGAAGGAAAGAGATCTTTTGGGGGCA TAGAGCTCATTGGTAGCAGAGCAGTTATTGGTCTTCTGTTCCCTATTTCAGGTCTCTTTT CATTATGCCACTCTTTATGGTGATAAGTATCATTGGACTTTCTTAGGAGAAAGTGGTCCT TTCCATAGCAACATCTCACTGATGAGGGTTGCATAGCCATCCTTTAATTATCTCCCCTGC CATCCTGGAAAAATGGCCCTCCCAAAGCCTATTAACTTGAAGGGTCTCTGTTGCCCCCTG GAGGCCCAGAGAAGAAGAGAAGAGAGGGCACCAATGCTGGGAAAGTCCCCAAGAACTGAT GAAATCCCTCCTGGGACAGATAGGGGCAGCCACAACATGGTGCTTCCCTCTTCAAAGAAG AATCCTAGAACTCCCTCTGCAGCATGTGGACTCAAAAAGTTGGGGTCATCTCACATGCAA GGAGGAGGCCTGCTCTCTGTACCATAGTGATTCCTAAAGGATCAGGCAAAATAATAACAC ACTCTTTTGGTGTGTTATTGCACACCGCATTTGGTGAATGATGCAGTCCACAGAAAGATC AACACATAGAAATTCAGGGTGGCCTGAAAGGCTCATTCTCTGCAGCCTCTCAAGTGCTGT GGCACTGTTTTACTACTCTGTAGTCGCATCTCTCCTAGAATTCAGGGCACTGGCTCATAA TTCTTTCTGCCCTCTCTTTACTTTTTAAGTGTAAAAGATAAGGCTGGAGGTAAACTATAC AGGGTGTGGTTCAATGCTGGGACAAGTTAAGAAAACACATGGTTTTAAAGGAAACCTCTC AGTACAACAGGACACACCTATCAAACCAAATATTACTAGATGGAACAGGACCAATTTGAG GATTTGCCAGAATTGAAAGGACACAGAGATCATTTAAATGTCGCCATGTCGAGGAGACAT GAAAGGCTAGAGATAGAGATAGTAACTGATTTGCCTAAGGCATCACAGCCAGGCAGAGGA AGGACTGGACCTAGAAGTCAGGTTTCCGACAGCCAAGGCCGTAGGCTTCCCTGTGGCCTG GAATCTGGAGCTCTTCTGTGTCAGCCCACATAACAGTCTATGCTGTGCTGTTACCCTAGT CCCTATTAAGCTCTATAATCCACTTTGTGTAAATACTACTAACCAAGGGACAACAAAGGG ATTGGCTGCCAGAGCGGAGTTTAAAAATCAACCTTAGCCTCTTACCAGCTGGGTGGCCTT AGACACCTCCCTTAGTCTCCCCAACCTCAATTTCTCATCCTCAAATACTCTCTTGTAGTG TCCTTGTGATAAGGTCTGATGTAAGGAATGGGCCTGGTGTGTTGTAAGTAATCACTAAAT AATAGGATATTAGAGTCATGGTCCAGTTGGTAATGTGCACAGCCGATCCCTAATGGCTCA CCAAAGCTGACTGTTAAATTTTGAAGAATTTTGCAAGCTAGCTGTGAACCATAGCCATTA TTAAAAATTAAATTATAGGCCAGGTGCAGTGGCTCACACTTGTAATCGCAGCACTTTGGG AGGCGGAGGCGGGGGAATCATTTGAGATCAGGAGTTCAAGACCAGCCTGGCCAATATGGT GAAACCCTGTCTCTACTAAAAGTACAAAAATTAGCTGGGCGTGTTGGCCTGTACCTGTAA TCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCCTTGAATCTGGGAGGCAGAGGTTGCT CTGAGCCAAGATTGTACCACTACACTCCAGCCTGGGTGAGAGAGTGAGACTCTGTCTCAA AAAAGTAAATAAATAAAAAAGAGATAAAACTTAAATTATATAAACAAAATTAAATTACAT TAAAATAAAAGGTAATAAAAATAATAAAAATTCATCAGTTTGTCATAATTTTTACTGCAT TTTTCTACTTATTTATGTTCTTAAAGTTACTTATGCCTATTTTATTTGTATGCTATACAA TGGTGCTCCACTGAGACTCTTGAAATTCATCATAATGGGAGTATTTCAAGCTAGTGAAAT CAGCAAATGCTATAAACCAACCCTTCTTTGGAGAGCTGAATGTTATACATTTACCAGCAC ACCACTAGTGCCAGCAACAAGAAGGAGCTGGAGCTGGATATCTGCCAGAGATTACCAGAA ATTAGATGGAAACTTTTCTTGCTTTTTTTCTAATCAGATTCTACATGCGCACAAATCCCT TCTACCCGGAAGTTGAGCTCAATTTCATTTCTGTTTTCTGGCCACAACTGCCAAATGGGC TTGAAGCTGCTTACGAATTTGCCGACAGAGATGAAGTCCGGTTTTTCAAAGGTAATCTTT CTAATTATTTTTCACTGCTTTAATAAATCAATTTTTCATTCCCTTTGGGGCTGAGATATA AGGTTACTAGCTACATTCTCTCCAGGGACTTTTGAAAATCTCAGTCTCACCAACCAAATC AATGAAAGTCCATCAACTTAACTAAACGGTGCGTAGCGCATTTTGGAGTCATTTTAAACA AAAGGCAAATGACTGGAGATAGAACGTTCTGGCCTTTTTAATGAATCTAGATTTACAAAA ATATTTTCTGCACAAACTATGTATTTAAAACCCCCTCCATATTCCTGGGAGTACTCAAAG TAAAACTCGAGACACTATGCCACGCACCAATATTTTTGCAAACGTGTGTTTAACGTAGTA CAATGAGTAAGACATTTGACTCAGCCATACACTCAAGGCAAAGAATTAAATGCAGGTCAG ATGGGCCAAACGCTTTGAAACAGGATTTTTAGCCTTTAAATTATGAAATTAAATGGATGT TAGAGACAGAAAGTTTCAAATTCCTTTTTCATGAGGGGTAAATAGCACGTGTGTACAGTA ACAGAAATCTTGGCTTTAGTATATGAGACCAGCTTTATGTGATGAGGGGCTTACTGAGTA TAAACACGGAATCTGGACACAGCATTAATTCAAGTATTTGGAACTATCTTCTAGTCAAAT GCAGTGATTTGAATCCAGGATTGCAAACCCTTACAGGTTATGAGTCACTACAGCACTTCA CCCTTTATGATACAAATGGTTTGAACTTCCACAGTCCATGAGCAAACCTGGAGAACCGAA GTTTATATCACCAAGGTGGCATAACTAACTCTTTAGTCATTTGAACATCTGACTGTGGAA AGAAGCCCCCAACTCCATAAACAAGTCATTCTCAAAGCTTGCTGCAGATTAGAATCAACT AAGAAGCTTCCAAAGATAGACACATTTAATTGGTCTGGGATAGGGTCCTGGCATCAGTAT TTTCAAAAATCTCCCTAGATGATTCTAATCTGCAGCCAGGGTACTGCACTAGCATGTGAA ACTAAGAACTTAGCTGAAAATTCACTTACTGCCTATTGAAGTCTTAGGCAAGTGTTTTAT CACTCTTTCTTGATTGGCAGGGAATAAGTACTGGGCTGTTCAGGGACAGAATGTGCTACA CGGATACCCCAAGGACATCTACAGCTCCTTTGGCTTCCCTAGAACTGTGAAGCATATCGA TGCTGCTCTTTCTGAGGAAAACACTGGAAAAACCTACTTCTTTGTTGCTAACAAATACTG GAGGTAAGTTTAAGTGCAGAGAATGTTAGGGCCTCAGTTCTTTCTACATAAAAAGTTCTA GAATAGCCCATTTCAAAGTGAGTCTCAAACTGCCTTGGCCGGCATCCTTTCCTTCAGATG GCTGGTGCCAATCTATCATCTATTTAGTCTATTGACCAATAATCATCACACAATGCCTGC ACTGGGAATCCAGAGAATGTAGGGGGATGAATTTTAAAAGGATGTAGAATTGAGGACATT CATCTTAACGGAGCTACTTTGGCCAAAAGTTACTTATCTTCCATAGTATGTTACCTCGAT AGGACATAGCGTAGAACCTACTGGAGAATTCGATGCTGGATTTCAGAGGGGCCTTAAAGG CCTTTTAGTTCACCCAACATTCCACCTTATCCCATCCACTCCCCATTTCACAAATGATCT ATAAAATGAAATATTCTGGTTAAATTCCTCATTGTGTATTTTCTGTAATGATTTTCAGAG TGCACATGTTTAGCAAAAGGTCTGACACTCTTAACTCTTTTCTGACCAGGTATGATGAAT ATAAACGATCTATGGATCCAGGTTATCCCAAAATGATAGCACATGACTTTCCTGGAATTG GCCACAAAGTTGATGCAGTTTTCATGAAAGATGGTAAGTGAATATACATGTATTTCCTCC ATTTCATTGCCGTAGCAATAACATCATTATTGTTAGTTGGAACAGCAAATGCCAAAAATA TCTGTGCTCACAGATGAATTGGTTTCTCAAGAATTCAAGTTAAACCTAGAAACTACTTGT ATAATGTAGTAAGTCTCTTTTGTTTTGTTTCTAGGATTTTTCTATTTCTTTCATGGAACA AGACAATACAAATTTGATCCTAAAACGAAGAGAATTTTGACTCTCCAGAAAGCTAATAGC TGGTTCAACTGCAGGAAAAATTGAACATTACTAATTTGAATGGAAAACACATGGTGTGAG TCCAAAGAAGGTGTTTTCCTGAAGAACTGTCTATTTTCTCAGTCATTTTTAACCTCTAGA GTCACTGATACACAGAATATAATCTTATTTATACCTCAGTTTGCATATTTTTTTACTATT TAGAATGTAGCCCTTTTTGTACTGATATAATTTAGTTCCACAAATGGTGGGTACAAAAAG TCAAGTTTGTGGCTTATGGATTCATATAGGCCAGAGTTGCAAAGATCTTTTCCAGAGTAT GCAACTCTGACGTTGATCCCAGAGAGCAGCTTCAGTGACAAACATATCCTTTCAAGACAG AAAGAGACAGGAGACATGAGTCTTTGCCGGAGGAAAAGCAGCTCAAGAACACATGTGCAG TCACTGGTGTCACCCTGGATAGGCAAGGGATAACTCTTCTAACACAAAATAAGTGTTTTA TGTTTGGAATAAAGTCAACCTTGTTTCTACTGTTTTATACACTTTC OMIM ID 120353