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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MMP3 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4314 Official gene symbol MMP3 Full name matrix metallopeptidase 3 (stromelysin 1, progelatinase) Aliases ,CHDS6,MGC126102,MGC126103,MGC126104,MMP-3,SL-1,STMY,STMY1,STR1, Gene summary Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq] Location Chromosome: 11   Locus: 11q22.3 Gene position 102714342 - 102706528  Map Viewer Gene orientation minus Gene size 7815 bp Gene sequence >MMP3:complement(6268944..6276758):Length=7815 CTACAAGGAGGCAGGCAAGACAGCAAGGCATAGAGACAACATAGAGCTAAGTAAAGCCAG TGGAAATGAAGAGTCTTCCAATCCTACTGTTGCTGTGCGTGGCAGTTTGCTCAGCCTATC CATTGGATGGAGCTGCAAGGGGTGAGGACACCAGCATGAACCTTGTTCAGGTAATTAACA CTAACTGACCTGGCCAGGTGGGGAGCTTCCAGAGTAAGCTGAAACCATTCTGTGTGTCTT AAAACCCACATAGAATGCTTGAGCTTACTGTGTAGGAACAGTTCAAGAATAGAGAGTTAT AGAGTGTTGGAAGTGGAAAAGGTCTCATTATCACACCATTTGGGCTTCTCCTCTTATGTA GGAAGAAACAAAGGCCAGAAATATTAGGTGTTTTCTTAAGATCACACAACACCATAGCAG TAGCAGCACTGGGGCTTAAGGCACATGAGTAACAAGTGGAGAGTGGATGAACCATATCTT GCTTTGGAACAGCTTCAGTTTTTTTTTTAATGCAACGTAATTTTAGCTAAATATTTGTGT TGCTAGTATCATATTATAAAATTTGCCATTATTTCAGCAAGCTAGAGAAATACTCCAAAT AGATTAAGAAGTGAGCAACTGCAAAAACTTACTATAAATAGATAGCTATAGTAAAAATTG TAAGAGTGACCTAAAAACTATACTTATTCTGTTAGAAATATCTAGAAAACTACTACGACC TCAAAAAAGATGTGAAACAGTTTGTTAGGAGAAAGGACAGTGGTCCTGTTGTTAAAAAAA TCCGAGAAATGCAGAAGTTCCTTGGATTGGAGGTGACGGGGAAGCTGGACTCCGACACTC TGGAGGTGATGCGCAAGCCCAGGTGTGGAGTTCCTGATGTTGGTCACTTCAGAACCTTTC CTGGCATCCCGAAGTGGAGGAAAACCCACCTTACATACAGGTAATGGTTCAGAGGGGTTT TCACATAAGATTGGAATTTTATAAACTATATCATAGGAGAAAATAGCATCTGCTTCAATT TTTCTCCTACAGGATTGTGAATTATACACCAGATTTGCCAAAAGATGCTGTTGATTCTGC TGTTGAGAAAGCTCTGAAAGTCTGGGAAGAGGTGACTCCACTCACATTCTCCAGGCTGTA TGAAGGAGAGGCTGATATAATGATCTCTTTTGCAGTTAGAGGTAAAAAAAAAAAAAAAAA AAAAAAAGCAAAACAAAACAAAACAAAAAACACATGAAATGTATCCATTCATCTATCTGG TGTTGTTGTACTGGAAAAGGCTCAAAAGGGATCCTTGTTACATATCTTTCCAATAAATTT TTTTCCTACTAGAACATGGAGACTTTTACCCTTTTGATGGACCTGGAAATGTTTTGGCCC ATGCCTATGCCCCTGGGCCAGGGATTAATGGAGATGCCCACTTTGATGATGATGAACAAT GGACAAAGGATACAACAGGTTAGTTACACATCTCTCAGAATGATTTTGGCATTAATTTTT TTATATGTAGAAATCTGTTAATAACCAAGAATGCTCAAGAAATGAGATGTTCTGGATTTT CCAGTGGATCAGAGATCAGCAGAATATATTTTTGTTTTAATTATTATTGAAAATATTTTC AGATGCTTTAACAGTTTTCCTATATTGGTAAGCACAATATAGGAAATATCATTAAGTATT TCTTTAATGACTGGATCTTTGTGATCTAGGGGTAACCATTATTAAGAAAAATTTCTCATA TCAAAATACAAACATTCAAGGGATAGTATATTGCACTGAATCTACATTAAAATGTGCTCT GGATGTTACTTATGTAATTTCCTCCATTTACTTCTTTACTCTTCAAACCAGAAATAAGAA TTAAATTTCAGAAACTGAGATTCTCTTTTTTTTTTTTTTCTGGCTGAGGCATTATTTTAG TACTTTTAGGTTAAAAGAATTTTTATGGGCTTGTTCTGAAGGAAAAGACTAACTCCCAAA TACAACGTTCAAACTGTTTAGGTAGAAGAATGTTTCTCAGTTCATAACTGTATGTTTTGG GGAATGACATCCAAAGTTTTCAAAAAAATCAGCTAAAACAATTAACACTACTTCTAAAAA AATAGGAAAACAATTAATACTATGTCTGAGGTTTAACTGGGATTTATAATGAAAATGTAA ACCTCTGTAGGACGTACAAATGTGAGTTTAGTCCTGGATAGAATTCTTGATTGGTTGAGT TAACGAATTCTTGTAAAGAAACCTTCCTGCAAACTCTCAAATGAGATTGTTCCTAGCATC ACAAGTTACACAAGTAATACTAGCAAAAGTAAGGTAGATTTACTTACTATATTGATCATA ATTACCCAATGCCTCCCAATTTTAGCATTATGGGTGTTTTTAAAAATATGAAGGAAAAAA TTTTGAATAAAGCCAGTGTTTATGTATTCTAAATCTGTTGTGTGACAAATGCTAGACATG ATTGGGCATACTGTGTTTTAAACCAATTTTGCAAATCCTATGACATCTATCATTATTCAT GTTTTTAGTCTCAATATGTACTTCATGATGATGAGGCTGAGACATTATCAATTAACATGA ATATAGTTTCCTTTAACTGAGACTGCAAATGGCAAATGTAAATATATTAAAACAGTGTTT AGCTTTGCATTGACAAATGAAGGTAAATATCTGATATGCTAAGCAAGTGGGTTCATTCCA TTCCTGAGTACAAGAAAAGGGATCTGGTTCTTCTGGAGTTAATATGCTTGTGAGGCTGGG GGTGGGTTTGGGGCCATGGGGGGCAAGTGGATGTAACTGGGAAATCAATCTCAAAGATTG ATTACAGGTATGAGTTTTAAAATACACTTAGCTTTCCATTAAGTGTGTAATTAGTCAATT GTTCAATTAACCAACAAACAAGGTGTAAAAAGCCCTGTGTGGTTCCAAGAAGTAAAAACC AATACAATGCACAGCAGACCTGTGTAATGCACATGTATTTAAAAAATAAGTAACTATTGT TCTCAATTTCTTAAATAGGGACCAATTTATTTCTCGTTGCTGCTCATGAAATTGGCCACT CCCTGGGTCTCTTTCACTCAGCCAACACTGAAGCTTTGATGTACCCACTCTATCACTCAC TCACAGACCTGACTCGGTTCCGCCTGTCTCAAGATGATATAAATGGCATTCAGTCCCTCT ATGGTGAGTGACACTGGGAAAATCAGCCATTGTAGTTTTGCAATGATGGTCTTCAGAAGA GCTTTCAAATGCTACATAAAGTATTTATGATTTAGTTCAAAGCACCGTGAGAATGTTTGG AAAGCATACAAATGGGCATATATTGAAACGTATCACATTTCCCCTAATGTTCCCTTTAGG ACCTCCCCCTGACTCCCCTGAGACCCCCCTGGTACCCACGGAACCTGTCCCTCCAGAACC TGGGACGCCAGCCAACTGTGATCCTGCTTTGTCCTTTGATGCTGTCAGCACTCTGAGGGG AGAAATCCTGATCTTTAAAGACAGGTCAGGCTGAAAAATTATATTTTCCTACCATTTTAA TCTACAATGTTTAGAAAGGAAAACACGCAGAAACTTGATAGAGATTCTTAGACATTTAAA ACAAAAACGTTTCTTCTGAGCTTGGAATCATTTAGATCTGGTGCTGCCTTTTCCCACATT TTCCTAAAATTGTCAGGTTCATTTTTGAAGGCACAGGCTGATCTGGTTCTTAGCTTCTAA TTGCTGTTTCCAAATGTCTTAAGTCACAGTTACTTTTCAAAAGGCATGAGTAGATCTTTC GAATAATAATTTTATTTTTACTTCCTTTAAAAATGACATCAGGATCAACATTACATTTAA TCAAGTAATTTACTTACTGATGGATCAATATGCACATGACAAACATTCAAAGAGCACAAA TGAGAAGCAAATTAAAAATTTTAGTTCCCAGTTCTCCCTGTACTCATCCAGAGTCAAGAC TTTTTGTGCATCCTTCCAGAATCTTTCTACACACATACAAGAATATATTTACACAGCACA TACACGTATACAAACACGGCCTAGCTTTTGGAAGAGGGTATAGCACACGCACTGTTTTGC ATACATTGCAGGTAATTAAAGCTTATGCTGGGCTAATTCATTTGCACGATAGAATAATTT TTCTTTCATAGAAGACATTACTCTGGAAACCTATGACGGGAGACTCACTACAGTCTTCTG AAGAAAAAGGAAAGAAATTTTCTAATGGCAATATACCTGATTTCTATCTGTCATCCAGCC TAGAAGATGAGAGAATGGGGGAAGCTGGGTGAGGCAAGACGGTGAGGAAAATATTCTAAA GGTGAAAGATTGTTTTTCAATTTACATTTCTTTTTACATATATTTTAGGCACTTTTGGCG CAAATCCCTCAGGAAGCTTGAACCTGAATTGCATTTGATCTCTTCATTTTGGCCATCTCT TCCTTCAGGCGTGGATGCCGCATATGAAGTTACTAGCAAGGACCTCGTTTTCATTTTTAA AGGTAATTACTATATCATCATTTGTTTAACTTGCCAAAGTAAACCCTCTCATAAGAAATT GAACAACACTTTAATTTTCCCTACTACAAGTTCTGGCTAATACAGTAGTCAACGGTAATG AAGAAATAACCAGGGCTGATATCATTGTATTTATATTTCATAGATGATAAAAATAAAGAC AAGAAGATAAATTACCCAGAGTTGTAAATTCTCTCATTTGACCTTAGTTCATTCATTCAG TCTGCAAATTTTTGTGAAAAGCCCACTGTAAGCTGGTGACTAAATCTAAAATTTGGGCTA CTACTTTACCATGAAAATCAAAGATGCTAAAGTGTATTTCTAAAGCGAAAGGGCTTAACT GTTATAATTCAATATGACTCTGAATTATTTATATTTAACAGGAAATCAATTCTGGGCTAT CAGAGGAAATGAGGTACGAGCTGGATACCCAAGAGGCATCCACACCCTAGGTTTCCCTCC AACCGTGAGGAAAATCGATGCAGCCATTTCTGATAAGGAAAAGAACAAAACATATTTCTT TGTAGAGGACAAATACTGGAGGTGAGATGCAAGAGAAATGACTTTGTATGGAGCCTAATT AGGGAAATTAGTTTCTTTTACTAAGGAAATCCCCCACCCCAACCTTAGGCCTGCTTCTCT CTTAGTAGGAAGGATGGGACTTCAGACAACTGTGGGAAAGTTCTTACTTTAAAACAGCAG CACCTTAGGCTCTCCTGCTTTCAGTCCCAAGTGCAGTTGGCTGGTGCTTCCCTTGGTGCT GTCACCCCACCTGCCTGGAGCCCCCTCTTCTCTCCTCAACCTATTCAAATCTTGCCCATC CTTCAAGTCCTGGCTCAAGTCTCATCACCTCCATGCAGCTTTCCCTCGTGGACTTTAGAC CCATTGGGAAAATGTTCTGAGAACCCAGACCGCAATTTAGCGTTCCCTTCCCATTGTCTT TTAGTTTGGCTCACTGTCTCACTGTGTGTTTGTCACTGTCTCATTGTGTGTTTGTTTTGT CTTCCTAACACTACTATATGATTTTCAAGGGCTACCTCTAACCTCACCCACTTGTCACCT CTACCTGATAATGATGGCTCATTTAAGAGATGATGATCAATAGCAGTCCAGTTTATGGAT ACAACCCAACACTCACAGACAGGTTGATTCCTGGGTCATTTGGCCAGACTTTGAGACATC GAGGCCGACCATCTGATATCCAGCCAATGGGCTAAAAACACACTTACTGTGCTTTGCTTC TTATCCTAATCCCTTTTCCCAGGAGGCCACCAGAGAAGATTTAGATGTGCAGGGGAGGGG ACAGCAGGCATATATGGGCCAATTGTGGTAGGGAATTAAAATTGCATTTTAGATGTTGAT TCAATTCACTTTATATATATGTTCACACTTTCATGTCTTTGTGACAGAAAGATGATTAAG GTTCTTTCTGTCCAGGCTTAAGAAATATGATGACAAACAGCATGTGCTACATACAGCAGG ATGCGGCCCCTGTTCCGGATGGAGATATGGCTTTCAGAACTCTTTACAGTACCATTAAAG TCACATATTTCTATAGTCCCAAATATGCTTGGCATTTATTTGCAGTATTTATAAAGTTTA GTAAAATTCCACATTAAACCTAACATGATCTAAGATGTTCGGTAACATGGCCTCTATGCA ATGCTGAGCTGTTTCTTTTACTTGGTACAGATTTGATGAGAAGAGAAATTCCATGGAGCC AGGCTTTCCCAAGCAAATAGCTGAAGACTTTCCAGGGATTGACTCAAAGATTGATGCTGT TTTTGAAGAATTTGGTAAGAGGATACTTACTGTGTTGGCCATAGAGCACTTGAAACATTT TATGATATCAGAGGGAAGAGGAGCATTGAAACTTTTTAATAACAAGTGTTTCTTAGGGCC AGTTCCCTTCTCAAAATTTTGATTCGCCTACATTTGTACTCATTATAGAACTACTTCACA AAATAACTTGTTTGGAACCATAAAGATAATTACACAAATCTCGCTACTTTATCTTATACA TGCATATAAAATCAAAGTGCTCCAGTGTCACTTACATCTCGAGCTAACATGTGGAGTCAA GCTCGACTTTCAGATTACCATGTTAGCATAAAAATCCCATCAAGTGGTGTGGCCAGGTTT AATGTTGGTTAGCTGGCCTTCTCCTCCACCCTATCTTATTGCTGCTACTAATTCCCAGGG AGATTTTTTGTCTGTCTTTCCTGAGTTGTCAGTCATTGCCCATGCCAGTCATTTGCAAAT ACTTACCTTTCCATGTGCCCAAAGTTTAAAAAAAAAAAAAGATTTTGTTTTCTACTCAAG GTAAGGAAGTGGAGGCTGATGATCTTTATTGAAAGGTAACCTGATCACCATGTTTGCAGA GCACTAAAGGGTCCCCTGGTGTTTTGAAATAGTTGCTGTGCTTCCTAGGCTGCAATGCAG GGAAAAGGGAGGAGGATTTTTGGGGAAGAAAGAAATAGGTGATGAGAGTTTCCAAGCAAG TGGAGAATTTATCTGATCGGAAGCAGAATAACCCTGTAACCTGGAATCTGGCTGTGTTTT CAGACAGAGCTGGCACCGAGTGCTGTCTCCATTCTTCCTTGCTGAGTAACCTTGAGGAAG CATCGAAATCTGTCTCAACCTCAACTTGCTCAATCTGTAAATGGAGTTAGACATACAACC TCATAGGGTTGTTGCAGAAATAAATGAAAATAAATTCATGTAACAAGCTTGGCATAGTCC CTGACATAAAGTAAAGCTCTATAAACACTTTCTATTTTTAGTTCTCTATGATTCTGAGTT TTGTATATTGTCAAATGTCTTTATTTGGAAAAATATCTTACTATTTCCCTTGTCTGTATT TGCAGGGTTCTTTTATTTCTTTACTGGATCTTCACAGTTGGAGTTTGACCCAAATGCAAA GAAAGTGACACACACTTTGAAGAGTAACAGCTGGCTTAATTGTTGAAAGAGATATGTAGA AGGCACAATATGGGCACTTTAAATGAAGCTAATAATTCTTCACCTAAGTCTCTGTGAATT GAAATGTTCGTTTTCTCCTGCCTGTGCTGTGACTCGAGTCACACTCAAGGGAACTTGAGC GTGAATCTGTATCTTGCCGGTCATTTTTATGTTATTACAGGGCATTCAAATGGGCTGCTG CTTAGCTTGCACCTTGTCACATAGAGTGATCTTTCCCAAGAGAAGGGGAAGCACTCGTGT GCAACAGACAAGTGACTGTATCTGTGTAGACTATTTGCTTATTTAATAAAGACGATTTGT CAGTTATTTTATCTT OMIM ID 185250