Entrez gene ID | | 4337 |
Official gene symbol | | MOCS1 |
Full name | | molybdenum cofactor synthesis 1 |
Aliases | | ,KIAA0381,MIG11,MOCOD, |
Gene summary | | Molybdenum cofactor biosynthesis is a conserved pathway leading to the biological activation of molybdenum. The protein encoded by this gene is involved in this pathway. This gene was originally thought to produce a bicistronic mRNA with the potential to produce two proteins (MOCS1A and MOCS1B) from adjacent open reading frames. However, only the first open reading frame (MOCS1A) has been found to encode a protein from the putative bicistronic mRNA, whereas additional splice variants, whose full-length natures have yet to be determined, are likely to produce a fusion between the two open reading frames. This gene is defective in patients with molybdenum cofactor deficiency, type A. A related pseudogene has been identified on chromosome 16. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6p21.3 |
Gene position | | 39902290 - 39872034 Map Viewer |
Gene orientation | | minus |
Gene size | | 30257 bp |
Gene sequence |
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OMIM ID | | 603707 |
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