Entrez gene ID | | 4353 |
Official gene symbol | | MPO |
Full name | | myeloperoxidase |
Aliases | | ,-, |
Gene summary | | Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q23.1 |
Gene position | | 56358296 - 56347217 Map Viewer |
Gene orientation | | minus |
Gene size | | 11080 bp |
Gene sequence |
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