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Gene information for MPO (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4353
Official gene symbolMPO
Full namemyeloperoxidase
Aliases,-,
Gene summaryMyeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q23.1
Gene position56358296 - 56347217  Map Viewer
Gene orientationminus
Gene size11080 bp
Gene sequence