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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MYBPC3 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4607 Official gene symbol MYBPC3 Full name myosin binding protein C, cardiac Aliases ,CMH4,DKFZp779E1762,FHC,MYBP-C, Gene summary MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq] Location Chromosome: 11   Locus: 11p11.2 Gene position 47374253 - 47352957  Map Viewer Gene orientation minus Gene size 21297 bp Gene sequence >MYBPC3:complement(47292957..47314253):Length=21297 AGTCCCTCTTTGGGTGACCTGTGCCTGCTTCGTGCCTGGTGTGACGTCTCTCAGGATGCC TGAGCCGGGGAAGAAGCCAGGTAGCTTTAGGACTGGGGTTGGGTCTAAGTGTGGGAGCAG GGGGGTGTCTACAATTGGGGAGCAGGGCTAGGAGGGAGTTCTTGAGGGGGTTGACGAGGA CGTGGCCTCTGAGCCCCAGGACAGGGGCAGCCAGTCCTCCAGGGTCCTTTTTTGATTCTC GGTTTCTTTTTCCCATCCCTCTGATGAGAGGTGAAGGTAAACCCAAGGTCAGGGACGCAG AGAGGGGACACAGCCAAGACAGGAAGCACCCGGGGTCAACCCATTCTGAGAATGCAAAGG GACCCCTTCCCTGTCCCATTGCCTTCACCTTCCACAGCAAGGTTCCCCGCGGACAGAGCC CACGTTTAGTATGGAGCTGAGCCAGGCTCACGGCATGCCTTCAGACCAGTCTCTACCCAC TATGGGTCTCAGTCTCCCAACCTGGGGTGCCGGGGGTGGTGGTGGCATTGGGTTGGTTCC TCCTGGCTGTGACATTATCTGCTTCATGAGCCTGTACGGTGTGGCCCCCATGTTGAGGGT GACACAGCCCCTCTTCTCTGAGAGAGGACAGTCAGGAGCCCCTGAACCCAGGCCAAGGGC AGGGAAAATCACAGCCCAGGGACCTGGGCCTGGGCTGTGCCCTTATGAAGGTTGTCCAGG GCAGAGATCCAGGTCCCCATCCCCCAGCGCCCTCCCAGGCCAGCTTTATCTCAGTTGCTG ATACCCAGCCTGAGGTCCTTGGAGGACAAATTTGGCCACATTCCAAGTAGGCAGACTTCC CCGCCCCCTGCCAAGGGCCCGAAATGGTTGGGGGAAAGGGAGCTGGGTTCATCACGGGTG TCTCCAAGCAGGGAAAGTGGACACATGCAGAAAAAGTCTTGTTGGGAGGTCAGGACCACA GCCCTGGCTCTCCCGACTGCTAGCTGTGTGATCTTGGAGGAGCCGCTTAGCTTCTCTGAG CCTCAGTGTCCTCCTCTGAGAAATGAACAGAATAACTGCAACTACCTCAGAGAACTGGTA GAGTATTACGTGAGGGGATGCATAGAAAGTGCTAGCACAGTATTTACTGAGAGGGGCTGC AGGGGCGGGGTGCACGCTCCAACCAGGGGCCGCTGTAGCCTCCACCTGGCCCTTCAGTCT CAGCTTTTAGCAAGAAGCCACGGTCAGTGGAAGTGGCCGCAGGCAGCCCTGCCGTGTTCG AGGCCGAGACAGAGCGGGCAGGAGTGAAGGTGCGCTGGCAGCGCGGAGGCAGTGACATCA GCGCCAGCAACAAGTACGGCCTGGCCACAGAGGGCACACGGCATACGCTGACAGTGCGGG AAGTGGGCCCTGCCGACCAGGGATCTTACGCAGTCATTGCTGGCTCCTCCAAGGTCAAGT TCGACCTCAAGGTCATAGAGGCAGGTAAGATCCTGATCAGCCTTCCCTGAGGTTTGGGCT GCTGGGGGAGGGGCAGCCCAGCGACTCTCCATCCATCCAGGGAACAGGAGGTGCTTTCAC ACTTTCTTGCCTTTGCTGTGGCTGTGCCCCCCGCCAGGAACGCCCTTTCCCCCTTTTCTG CACATGACCTCTCTGAGTACCCCCATGTGCCATCCTGGCTTGTTCCAGCCATGGGGTAGG TGGGAGAGATGAACAAGACACAACCCCACTCTCCCCCTGCAGACCTCCCTGGGGAGATGA CCCTGCACAGACGGCCGGGAAGCCCCAGGAGCTGTGGATGAGGGGAGTGCAGCCCAGTCT GAGGGGCTGCTCTAAGGCTGGGGCAGAGCAGGGATGGACCTGGAGCTGTTCAGGGCAGAT GCAGAGGACATGGGAACTGATGGCCTGGGACGGGGAGGAGAATGTGAGAGGCAGGCTGGC TCTCCAGCTCAGCATGAGCTGCCTCTGAGGGGCCCAGGCAGCGGGAGGACAGCCATGGCA GACTTTCCTCATCCACAGCGGGCTCATGGGTCCAATGCTCAGGAGAGAGAGGGTGGAGGG GTCTCTGGTTAGTGGCTGCACCACGACTCCCATCTGATCCCCTCCAGAGAAGGCAGAGCC CATGCTGGCCCCTGCCCCTGCCCCTGCTGAGGCCACTGGAGCCCCTGGAGAAGCCCCGGC CCCAGCCGCTGAGCTGGGAGAAAGTGCCCCAAGTCCCAAAGGTGAGAGGGGCTGGGCAGG GAGGGGCAGGATCCGTGGGTAGGGCGTGTCCAGGGCAGGTCTCAAAAGCCTTTGCTGGGC CAGGTGCGGTGGCTCAGGCCTATAATCCCCAGTACTTTGGGAGGCCGAGGTGGGCGGATC ATGAGGTCAGGAGATTGAGACCATCCTGGCTAACATGATGAAACCCCATCTCTACTAAAA ATACAAAAAAATTAGCCGGGCGTGGTGGCGGGCACCTGCGGTCCCAGCTAACTTGGGAGG CTGAGGCAGGAGAATGGTGTGAACCTGGGAGGCGGAGCTTGCAGTGAGCCGAGATTGTGC CTCTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCATCTCAAACAAACAGAAAAAGCCT TTGCTCACAGGGTCAAGCTCAGCAGCTCTCAATGGTCCTACCCCTGGAGCCCCCGATGAC CCCATTGGCCTCTTCGTGATGCGGCCACAGGATGGCGAGGTGACCGTGGGTGAGTGTGAG CTGCTGTGCCCAGCATTGGGGTGGGAAGGGGGGGCAGCAGGACACTCCCCAAGCCGGGCC TGTCGCCCCTGCCTTTGCAGGTGGCAGCATCACCTTCTCAGCCCGCGTGGCCGGCGCCAG CCTCCTGAAGCCGCCTGTGGTCAAGTGGTTCAAGGGCAAATGGGTGGACCTGAGCAGCAA GGTGGGCCAGCACCTGCAGCTGCACGACAGCTACGACCGCGCCAGCAAGGTGGGTCCACC GGGGTCGTGGAGACACGGAGAGAGGGGACATGGAGAGCCCTAGAAGGCACAAGGCACACA GAGGGCACCATGAGACCCAGAGGCACACACGAGCTGCAAGCAAGGGGTGTGGGGAATCTG GGAGGCAGGTGGAGGGGCCAGGGGCCCACAGGGAGATCCCGGAGGCCTGGGGGCCAGGGA GTGCGATGAGGCTCATGGGAGCACTGTCGGGGACCTGGGAGACTTGGTGGACATGATCAC CTCAAGGGGGCACCTAATAAGGTTTGGCCGGGGGTGGGGGGTCGCCCAGGGTGGTCAGGA AGCCTGGAGGACACTGTGAAGCATGGGGGCACCAGCTAGTGGGGTTGTAAAGCCCCTGGA TGGGTGAGTATCAGGGCTAAGGGCTCAAGGGACTCTCAGGGATTAACCAGAACAATTCCT CATTATACAGACACGGAAACCAAAGCTTGAGAGGTTAAGTGGCTGCTCCAAGGTCACTTA GACATAGGCCTAGAACCTTAAGCCTTCGTTTTTTGTGTTTTGTTTTTTTCCGCCCTGCCC ACCAGAACCTTAAGGCTTAAGTCCCCTTGTTTGTTCACTCCAAGCCTCTGCTTTTCCCAA CCTTCCCCAGTCCTGGGCTAGGCAAGGGGGCCTCTAGCAAGAGAGGCCAACATGTTCTGC TGTGCGGGGCTGTGCATTGCACAAAAGCCTGTATTTCACCACAACCATGTGCCAGCAGAT GGCAATCATGGGTTTCGAGATAGTCCCCTTTCTCTGTACAAAAACTCTGTATGGGTTAAC TAAAGCCTGAGGGTGCGAAGATCGATGAGCATTTGTCACTCCCAGCCTCCTTTAAATATA TATATATATATATAATTTGAGACAGGGTCTCGCTCTGTCGCTCAGGCTGGAGTGCAGTGG CTCAATCTCGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCGATTCTCCCACCTCAGC CTCCCGAGTAGCTGAAACTAGAGGTGTGCACCACCATACTTGGCTAATTTTCGTTATTTT TAGTAGAGACGGAATTTCACCACGTTGGCCAGGCTGGTCTGGAGCTCCTGGTCTTATGTG ATCCGCCCGCCTCAGCCTCCCAAAGTGGGGATTACAGGCCTGAGCCACCGCGCCCGGCCA CTCCCAGTCTCCTTTAAGGGTGCGGAGCCTTGTCTCCCGGCCCCTGGTGTCCCCTGACGC CCCGTCCCTCCATGCACACAGGTCTATCTGTTCGAGCTGCACATCACCGATGCCCAGCCT GCCTTCACTGGCAGCTACCGCTGTGAGGTGTCCACCAAGGACAAATTTGACTGCTCCAAC TTCAATCTCACTGTCCACGGTGAGGGGGCCCTGGTGTCTGTCCTGGGCTCGGGCTCCCCA TGGGTCCTGGTCTCCTACCTCCTTTTCCCAACACTAAGGAGGATGCCTCGTCCCATCCAG ACATGAGTGCTGGCCACGTGCCCAGTGCTGCACACACAGGGTGTGAGAGAAACCCCAAGG CTTGCAGGGTAGGCGTGGGGGCTTAGGGCTGAGTCCGGGTCTCATCTGGGTGGGACTCTG TTTTATCATCTTGGTGTCACGGCTCCTGGCCCATGGCCTGGCACTGTCTGAATGTTTGGG CGATGGGTGAAGGTGAGTTGAGAGATGGGTGGGAATTGGGGACAATAAACCGTCCCACCT GCCTGGTACCTTGACCCTGGGAAAGGCTGGGAAGGTGAGATCCTGGGGCAGATGCCCAGC CTCATGGGGTCATGAATGGGCAAGTCTGTGAATACTCAGAGGCCGCCCCCAGGGCAGGGC TTCTCAAACGGCCCCCTCTGAAGCCCCTTCCCCCATCTCTCCACCCTTTGAACCCAGAGG CCATGGGCACCGGAGACCTGGACCTCCTATCAGCCTTCCGCCGCACGTGAGTGGCCATCC TCAGGGCCTGGGGGAGGCCAGTGCTGGAGTCTGAGGCCCTTCAGGGTCTCGACTGGGGGT CAGGGCTGGGGATGATTTGCGGGGCGGAGCTGAAGTCAGTGGGGGCTGCAGGGGAGAGCA AGCTTCCCAGGCAGGTGAGGATACTGAGTCTAACCCCCACAGGAGCCTGGCTGGAGGTGG TCGGCGGATCAGGTACCCCTGCCCCAGGCCCTACCTGCACCATCCGCAGACCCCCAGGGG TCTGAGACGGGTGGGAGCCCAATCTGGCTAGTGTCCCTTTCTCCCTCCCCACTCCACTCC CATCCTGCTCCTAATCCCTTTCCAGTCCCTCACTGCAGCCTCACTGGGGGTCCCTCTCCA TAGTGATAGCCATGAGGACACTGGGATTCTGGACTTCAGCTCACTGCTGAAAAAGAGGTG AGTCCTGGGTGGCAGTTCCTGGGGCAGCTGGTGAGGCCTGGCTCCAAATCCCAGCACTGT GGTTTGCCAGCTGTGTGACCCTGAGCACAACACTGCACCTCTCTGAGTTGGTTTCCTTGT CTGTCGAGGGGATGATCCCAGTGTGGAAGGAGTTAAAGGGCTCTGCAGACATTATGTCCC GTCAACAGTCATCCTCACAGTGTCCCCCACGGCCACTCCACACTTGAGGCTGCAAAAGCT CCCTCCGTAAACTCCGGGGACCCAGAAGGAACAGAGAGAGGGTCCCCAGAGCTGCAGGGT CTACCAGGTCGGCCCAACTGACTTATGTTCTCTCTGCCCTCTCTCTCCCTCTCCCCCGGC CCCTCCATTATGGCTGCTGCTGCTGTGGCCCAGAGAGTAAGAATCGGGGTCTGGGTGTTT GGGGGCGGCAGGGCGCTGGTGGGTGCAGAGGGGATTCCCGTCCCCTCTCTGAGAGGCTGT GGTGAGAGACTCAGAGCAGGGTGCGGCTCCCCACGGACAGGGGTGAGTCTCTGTGCCTTG GGCTTCTCCTGCCACCCACCTATCTGTCAGAGCTTAGGAGGGATAAGAAAAAGTAATGCA CACAGGAGGTCCTGCCAGAGCCTCCGGAGCAGCATGGGTGCCCCACAACACAGGGAGTGC AAGTGCGGAAAATAGGGAGGAAGTAAAGGCCCATGGGTGGGGTCCAGGTCTTTGAGGGAA GGTGGCCATACCTCTCATGTGCCACCTACCCTTTCTCCCACCCCCACCCCTGGAGCAGCA GTTTCCGGACCCCGAGGTGAGTGCCCAACATAGCACAGCACCCTCATCACCCCTAATTCT GCCAGGAGCCCCTCCAGATCCCCAGCCCCTCTTCAGCTCCCTTGGCCCCCAGTCCTGCCT GGCCTGGGACCCAGAGCAGCTCCAGCTGCCCCACCAGAAGGGAAGGGGCAGAGGGACAGG GGTGGCTACAGCTCCTTGGTCCTGGGCCCAGGAAGCCCCGCCCAGGGGGCTGCAGTCTTG CCCCCGGCCACAGCCTAGACTGCGGGACACAGGGACTCGAAGCTGGAGGCACCAGCAGAG GAGGACGTGTGGGAGATCCTACGGCAGGCACCCCCATCTGAGTACGAGCGCATCGCCTTC CAGTACGGCGTCACTGACCTGCGCGGCATGCTAAAGAGGCTCAAGGGCATGAGGCGCGAT GAGAAGAAGAGCACAGGTTAGCCCTTCCTCAGAGGGGAGAGGAGAGGGCACAGGCTAGCC CTTCCCTACACAGGAGAGGAGAGGGCATAGGTTAGCCCTTCCCCACAGGGGAGAGGAGAG GGCACAGGTTAGCCCCCCACCTCGTCCACATACATGGAAAGAGCGGAGTCCGGCTTAGCA CAGAGACTCACAGGAAAGAAGAGCCCAGGTTAACCCCTCCTTGTGTAGAAAAAGCCAAGA ATGCCCAGGTTAGCCCCTTACCACAGAGATAGAAGAGAAGAGCAAAAGTTAGGCCAGGAC AGCCACAAGGAAAAGGACAGAGCTCAGGTTAACCCTCCTCACCAAGGAAAAATCAGGCTA CACTTTCTTTCTCTACCCTCTTCTGAAAAGAAATGAAGCCCGGTTAACCCTCTCCACACC CAAAAGAAAAGGGAAGAGGCCCGCTAAGCCTGGAGAGCCACACACAGGCAAAGAAAAGAG CCTGGCTAATCTTTCTCTCAGGCAAACAAAGCAGGAGGGCTTGGGTTAACTACCCTCACC CCCAGGCAGATGGAAAGAGGAGAGCCCAGGAATAGCCCTTCTCCACTGAGGGGTTGACAA GGGCGGGTGTGAGCCGGGAAAGCAGGGGTCTCACATGCCTTCTCCCCACCATGTCTGGGT CTAGCACAGGGCCTGGCACACACCTCGAGCGCTCTATAAACACCGACTGAATGGAGGGGT CAGCTTCCATGCAGGATATGGGAGACAAGCCCCTCCCAAAGCACACACACAAAACACACA CGATCATGGGGACGGGGAGAGGAGCTGGTTAGTCCCTCCCTGCTGACCTCCCCCAGGCCC CTTATCCCTCTGCCCTGCCTCCCTGTTGTCTCAGCCTCACTGGGTTTCCCATCACCCCAT CGCTAGGTGGCCTGGCCCTTACCGGCACCGTGGCCCCATTTAAGCCAGGGATCCCCTGAA TGCCACCAATGTTCCTCTGGGTTAACTCCTGAACTGCTGAGCCCAGAGGGCACCAAGCAA AGGACTGTAGGTGCCCAAGGAGGAAAAGATGGAGGCTGGCAAGGCAGATGGGGACCTCCG AGGGTAGGGGTGTCTTCCAGGAATAGCAACAACAGTAAAAAGAGCAAATTGCTGGCCAGG TGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACCTG AGGTTAGGCGTTCAAGACCAGCCTGACCAACATGGTGAAACCCCGTCTCTACTAAAAATA CAAAATTACCTGGGCATGGTGGCAGGCGCCTGTAATCCCAGCTACTCCGGAGGCTGAGGC AGGAGAATCACTTGAACCCGGGAGGCAGAGGTTGCAGTGAGTCAGGATTGTGCCATTGCA CTCCAACCTGGGTGACAGAATGAGACTCCATCTCAAAAAAAGTGAGTGAGTTCCTTCCTA AGCCAGCCACTAGGTGCTTTATGTAATTATCTCATTTAATTCTCGAAACAACACTATGAT GGAAGGACTATTACCATTTCCATGTTACTGAGGAAACCGAGGCACAGAGGGTTTAAGGAA CTAGCGCAAGGTCACAGAGCACCCAGCAGTAGATCTCTGCCCCTCCGCAGCTGACTCCAG GCCCAGCCAGAGTATTTGAGGACTCAGGGGTCCTTCTCTGCTCGGTGGATGGAGCCCCCA CTTCCTCCCTGGGCTCAGCAGCAGCAACATGGGCTTTTACAAACACGGCCGCAAGAGGAG GCATTGTTGTGGAGCAGGGCTGGGCTCAAGACCCAGCTCTGCCACACACCTGCTGGGCTG GTGGCATTGGGCCAGTCGCCTCTCTGAGCCCTATTTCCCCCACTGCAGCAGCATGGGGAC CACCGCACTGGCCCTGGGGGCTGAGATGGGAGTGAGAGTGCTGGGCACAGAGGGCTGCTA GGTGGGAGCGCCTGGGAAGAGTACACAACTCAGGGGTTGCTGAGAGAAGAGAAGGCACAG CTGTCCCAGCCCCAGTTCTCCTGACAAGCTTCTGTCTTTCTGGAAGCCCCTAACCCAATC CCTGAGCTGAGCAGGTGGAGAGGACCCCAAGGAAGACAGAAGGACAAGGTCAGACAGACA GAGACAAGGAGGTGGGTTGACACATAGACACAGATAAAGAAATGAAGACACCATGCCTGT AATCCCAGCACTTTGGGAGGCTGAGGCGGGCGCATCACCTGAGGTCAGGATTTCAAGACC AGCCCGGCCAACATGGTAAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTG GTGGCACATGCCTGTAATCCCAGCTACTCGGGAGGCCGAGGCAGGAGAATCACTTGAACC TGGGAGGCAGAGGTTGCAGTGAGCCAAGATGGCGCCATTGCACTCCAGCCTGGCCAACAG AGCAAGACTCTGTCCAAAAAACAAACAAACAGACAAACAAACAAAACAAAAAGAAATAGA GACACAGAGAAGTGGAAGCGGGGCGGCACAGAGGGGATTGGAGGGGGGGACCTGGGCCCC AGCCACAGCCACAGTAGCTTGGCCTGGGGGAGCAGGGTGCGGGCGGTGGGGTGGCCGGGG CTGAGGGGTGGTGCTCAGCCTTTCAGAAGAAGCTGGAGCCGGCCTACCAGGTGAGCAAAG GCCACAAGATCCGGCTGACCGTGGAACTGGCTGACCATGACGCTGAGGTCAAATGGCTCA AGAATGGCCAGGAGATCCAGATGAGCGGCAGGTGCAGCCTGGGGTGGGGAGGGGGGCTCG GGTGGAGGTGGGGACCCCCATAGCCTTGCCTCCTGCCCCTCTCCACATGCGTATCTCTGA CTCGGTGTGGCTCTCAGCCCCATCTCTCTGGGCCTAATTTCCCATCCTTTTGCTCCTGCC GGTCCCTCTCTCTCTCTCCTTTTGTCTCGGGCTCACTTCCTCCCGTCGGGAACACTTCAA CGGCCCCTTCTGTTCTACAGCAAGTAAGTTCCCCTCTGGATGGCTTGGGGTGGGGGGCAC AGGGATTATCATGGGGCGCACTGGGCCCGGAGGGGTGTCCGCAGCTTTCCTGCCACTTCC CTGCGGCCCCCACCCAGGTACATCTTTGAGTCCATCGGTGCCAAGCGTACCCTGACCATC AGCCAGTGCTCATTGGCGGACGACGCAGCCTACCAGTGCGTGGTGGGTGGCGAGAAGTGT AGCACGGAGCTCTTTGTGAAAGGTGGGCCTGGGACCTGAGGATGTGGGAACCTGGGGAGG AGATGGCCTCAGGGGAGCCAACCCTCATGCTCACCCTGCCTGGACAGAGCCCCCTGTGCT CATCACGCGCCCCTTGGAGGACCAGCTGGTGATGGTGGGGCAGCGGGTGGAGTTTGAGTG TGAAGTATCGGAGGAGGGGGCGCAAGTCAAATGGTGAGTTCCAGAAGCACGGGGCATGGG TGTTGGGGGCATCTGCCCAGAAGAGGCCACAGCACTTGCCACCCACCCACCCGGCTAGGC TGAAGGACGGGGTGGAGCTGACCCGGGAGGAGACCTTCAAATACCGGTTCAAGAAGGACG GGCAGAGACACCACCTGATCATCAACGAGGCCATGCTGGAGGACGCGGGGCACTATGCAC TGTGCACTAGCGGGGGCCAGGCGCTGGCTGAGCTCATTGTGCAGGGTGAGCCTGGCTGGG GGGGCACATGAGGCTTTAGGGCTTGGACCCCTCAGCCCCCACCCCACCTAGCCCTGTAGG GGAGCAGGCAAACCTGGGCTCAAGGCCTCTGTGACCTTGGGCCTTTGACAGCCTAAACCT CATCCTTCTCATCTCTAAAATGACGATGCTGAGGTGACCGCTCCAGAGGGTACTGAGAGG GTCATACGGGCCTGGTGAGCATCACCACCCCTCAGACACTTGAGGTTCCTTATGTGCACT GCACCATCACAGGCAAACATGGCACACACAGGCACACGTGTTTTCACATGCCCACATGCA CCCAGACACGTGCGCACCAGCGCCCATGGGCCCACACGCCCTCCACAGGGATTCACGCCA CACCCACACACCCTCCCGAGCTCAATGGCTCTGCCCTGCCCTGCAGAAAAGAAGCTGGAG GTGTACCAGAGCATCGCAGACCTGATGGTGGGCGCAAAGGACCAGGCGGTGTTCAAATGT GAGGTCTCAGATGAGAATGTTCGGGGTGTGTGGCTGAAGAATGGGAAGGAGCTGGTGCCC GACAGCCGCATAAAGGTGTCCCACATCGGGCGGTGAGTGTGCAGGGCAGGTGGATGGGAC AGGTGGAGACTGAGATGGAGACAGAGAGAGACACAGGGAGAAACAGAGAGAGAGAGATAA AGACAGGTGGACAGAGAGGCAGATGCACAGAGACAGGACAGAGACTGAGACAGAGACCCA CAGAGAGGGAGAAACAGACAGACCCAAAAAGACAAAGAGACAGAAAGACAGAAATAGTTC TATAGAGACAGAAAGATATGCACAGGGAGGCACACACATAGGAGAGTTCGTCAGAGACAG AGAAGAACAGAGGGACAGAGACAAAGAGGCAGCAGGGAGAGACACGGACGGGGTCGAGCG CTCCCCAGCACCCTCCCCCAGCTTGTGACCAGGGCAGGGCAGGAGGCCACCAAGGAGGCC GGCTCTGGCCAGAGGCCCTCACTGCCTCTCCCGCCCTCTTGCTCATCCCTGGAGCAACTG GGCTGGCCGTGCTGGGCCCAAGTTCACAGAGATTAATGAGACCCAGCCCCTGCCCAGTCT CCAAGGGCCCAGCCAAGGAGATGCTTTGATGTAGAAATCACTTTTACGCTGCCTACCTCT GAAGGCACATTAAAAAGCTGGAAAATTAGATAATATAGAAAAAAAAAGGCATTTTTAAAA ATCAGAATACCAACAAGCCAGGACAAGGTGAGGGCCTCCTGGGACCCTGGCTGGGGTATC TGGCAAGGCCAGGGGTGTGTGGCCCAGTGGGGTCCCCTGAGCCACTGCTCCCCTGCAGGG TCCACAAACTGACCATTGACGACGTCACACCTGCCGACGAGGCTGACTACAGCTTTGTGC CCGAGGGCTTCGCCTGCAACCTGTCAGCCAAGCTCCACTTCATGGGTGAGCCTGCTCCAG GGTAGGGTGGGTCGGGGCAGTGGGGCCAGGAGCCCCTGTCACTGGGCCCTGCCTTTGCCC CCGTGCTACTTGCTCTTCCTTCTCTTGCAGAGGTCAAGATTGACTTCGTACCCAGGCAGG GTAAGTCTTGGGGCCCCTGAGTCTTGGTTCTGCTCACTTTCCCGCAACCCACCCACGCAG GCCTCCCCTCCACTCACAGAGGGAAGAGCAAGGATCAAAAGTGGGGGTCCTGGGGCCCAG CTTCAGCTTTGCCACTCATGACCATGGGTCAATTATAATCTCTGTGAGCCTCAGTTTCCT CTTCTCTAAAATGGGAACCCTGATAGTGCCACCTCATAGGATAGTTATAAAGATGAGGTG ACATGATGTATCAGACCTGTCAAGTGCTGTCACATGTGTGACTGTTATTATTACATCTTT TCTTCTTCTTCCTTTTTTTTTATTTTTATTTTTTTTGAGACGGAGTCTCCCTCTGTCGCC CACGCTGGAGAGAAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCCCAGGTTCACA CCACTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCCGCCACCATGCCCA GCTAATTATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGATGGTT TCGATCTCCTGATCTCATGATCTGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGC GTGAGCCACTGCGTCCAGACTGCTTTGCTTTGTTTAACTGAGGGCAGATTCCTGATTTAT TTGGCCAGGGAACCTTTTTAATGTGTGCATGTGTGCGTGCATGTGTGCGCGCGTGTGTGT GTGTGCATGTGTCTGTGTGTGTATGTATATATGTGTGTCTGTGTCTGTGTGTGTGCGTGT ATGTATGTGTATTTGTGTCTGTGTGCATGTGTGTGTCTGTGTGTGCATGTGTGTATGTGT ATGTGTGTCTGTGTGTATGTGTATATGCGTGTGTGTGTGTGTATTGTGTGTGTGTGTATG TGTGTGGCAAGACACTGATGTTCCCCCAGTTTTCAAAATGCTATGCTAGGTGACCTGACC TGAATATTACAAGCCTCCCAGCCAACGTCCTGGGGTGATGGGAATGTTCCAGATCTTGGT TGGATTAATAATTGCATGGGTGTATTCATCTGTCAGAACTCAGCCTACTGTCAGATCTGA GCATAAACTATACCTCAATACAAATCTAAAAAACCAATAACCAGGGGCCCAGGCTCTTGA GCAGCCCCGCCCCAGTGACCTGTGCTCCTCCTGGCTCTCCCGTTTCTCTGAACTACATTG TGTCTTCTGCAGAACCTCCCAAGATCCACCTGGACTGCCCAGGCCGCATACCAGACACCA TTGTGGTTGTAGCTGGAAATAAGCTACGTCTGGACGTCCCTATCTCTGGGGACCCTGCTC CCACTGTGATCTGGCAGAAGGCTATCACGCAGGTACTGTGGGTCCCTCCTCAGTCTCCCC ATCTATAAGATGGGTGTGTGGAACCAGCCAAGTGCTAGGACCTGCTGCACACCCCACCCA CATGTGCACGCCCTGCTGTTGGCTACCCCATGGGAGAGACTGGTCAGGGGGCAGGCAAGG TGGGCAGTGTGGGTCAGGGGGTGGAAGAAGCAGCAGAGGGGCGCTTCCAGGCTGAGTCAG CTCCTCTGCTCCCTACTTCCCTCCTGCCCTGTTCCCAGGGGAATAAGGCCCCAGCCAGGC CAGCCCCAGATGCCCCAGAGGACACAGGTGACAGCGATGAGTGGGTGTTTGACAAGAAGG TGAGTGAGACTGAGGTCAGGAGGAGGCTCGTTTGTCTTTCATCACTTTCTACCTACGTGG TGCCGAGCCCTTGGCGAGGTCTCCATGGAGGTGCCACACTTGGCCGGGTGTGTTGCTGCC CCCAGCAGGGTCCCTGTGGGGCCCTCACACCTCAGGCAGAGGGTCTCTGTGAAGTGTGCT GATGGCCATCACAAGGATGTGGACACCCTCTCATTGCCAGGAAGCCCTCATGACTGGGCT GCTCCCTGGCTCCCTTCATCCTAAGCTGACCTTGACCTTGACCTTGTGCTCCCTCTCAAC TCAGGAGTAGTTTCTGAGACACTTTTCTGCCAGTGTAGCTGCCGGGGTCTTGCTCCTGCC TGGCACTGTTGGTTCTTCTGAAGGCTGGGGTCTTGAGGGGTCCTCATGATAGCTCATCTG AGAGGACAGGTGGTTGCCCCAGGTCCCGTGACAAAGCTAGAACCCGAGCCCCTGCCCTCA GTCGGTGCCACAGAGATGATTTTGAACTAGATGCTGACGTGGATGCAGTCTTCCCACAGG CTGTGTTCCCCCCATGGACCCCCGGGACATCTGGCTGTTGGCGGAGGCTGCAAGGGCCTC TGGGGTCTGACTTGGATCTCACCCCAACTCTGCACCCCCCCAGCTGCTGTGTGAGACCGA GGGCCGGGTCCGCGTGGAGACCACCAAGGACCGCAGCATCTTCACGGTCGAGGGGGCAGA GAAGGAAGATGAGGGCGTCTACACGGTCACAGTGAAGAACCCTGTGGGCGAGGACCAGGT CAACCTCACAGTCAAGGTCATCGGTGAGGCCGGCCGGGGTCCAAGCTGGAGAACACAGAG GGGCAGCCCCAAGGAGGGCCCATCCGTTCGCTCATTCAGCCACTCGACAAACATCACGGG CATGCTCCCTGAGCCGAGCGGCAACAGGACAGGTTTTTCTGCCCAAAAGGAGCCCCGCTC TGGGGGAGATGGAGGCAGATGCATCCAGCAGATTTCCTGCGACACTGCTGTACATGAGCC ATGTCCAGAGTGCCGTGGGAGCACTGAGCAGAGAGCCATCCCTGTGCCTGGGGGTGATGC CTTTAGGAGGCTGAGAAGATGGTGAGGAAAGGCATCCCAGGCAGAGGAAACTGTGTACAA AGGGGTGGAGGAGGGAAAGGGCCTTTTGGGTGTGGAGAATGAATGAAACATGTCAGGAGA GGACTGGGTGGGGTTGGGAGGATCAGAGCCAGGACAGGGGTGAATATGGGCAGTGAGAAG CCTTAAAGGGTTGACGGAGGGCTGGCGACATGATCAGAAATGCATCCTGTTGAGACCCAG CCTGGACAACACAGTGAGACTCCATATCACTAAAAAAAAAAAAAAAAAAAGGAAAAGAAG AAAGAAATGCATTCTAGAAAGATCTCTTTGGATCTGGGGGTGGTGGGGGCAGCCTGTGGC GGTTAGTTGGAGTGGGAAGGGGACGAGCAACGTTACTCAAGGCCCTGAGCGGGGCAGGGC TGATGTGGGTCCATCCCACCCCATCCAGACGTGCCAGACGCACCTGCGGCCCCCAAGATC AGCAACGTGGGAGAGGACTCCTGCACAGTACAGTGGGAGCCGCCTGCCTACGATGGCGGG CAGCCCATCCTGGGTGAGTGCAAGGGCACCGGATGGAGGTGTGAGGGCGCCAAACAGATC CGAGGGAAGGTGGTGTGGGGATGCCTGGGTTCCAGACCAGAGCTGCCACCTCCCCTGAGC CAGGCTACATCCTGGAGCGCAAGAAGAAGAAGAGCTACCGGTGGATGCGGCTGAACTTCG ACCTGATTCAGGAGCTGAGTCATGAAGCGCGGCGCATGATCGAGGGCGTGGTGTACGAGA TGCGCGTCTACGCGGTCAACGCCATCGGCATGTCCAGGCCCAGCCCTGCCTCCCAGCCCT TCATGCCTATCGGTGAGCCTGCCTGGCCTGGTCCTGCCCCCCGCCCCCTCCCCAGTTAAA AACCTCCAATAATAGCAGGTGCTCTGCAGGCAGCCATGCTAGACACTCACATCCACAGTC TCCTTTCATCCTCGACTGGGGATACTCAGCCGCATTTTACAGATGAGGAAACAGGCTCCA AGCAGTTAAATGACCTGCTTGAGATCTCCCAGCTGGTTGGGGTGGAGCTGACTCTCACAC TACGCCGACCCCTAGTTCACGTTTCAAGCCTCTCTTTCCATGTCTACAAAATGGGAATAA TGACACTGCCTATCTCAGAGAGCTGTTAGGATGATATGGGATGACCAGGCAGGCCATCTG GCATCTAACAGGTGCTCAATAAATGTTCATTGTCCCCTGTTCTCCACACCCTTCAACCCA GGGTTTTCACCTATGGGATGGGGCAAGGGCTGTAGTTAGTGGAGGGGTCTCAGGGGCATC TGTCTGTGGAAAGAGTCCTGGACCAAGACTCAGAGATGGCAGAGGCAGCTCCATGGTCCC CGGGGGGCCAACTGGAGTCATCCCTCCCTGAAGCCTCAGCTTCCTCATCTGTATAATGGG GTCTGAGTGGGCAGAACAGGTGTTGAGACTGTGGCAGGGCTCAGGAGGACACCTGTTCCC ACTAGGGTGGGTGAGTCCGGGGGCAGCTGCCTGTGGCAAGGGCAGGCCAAGGACCCCTGG GCCCAGGGATGGGGCACAGCTTGGGAAGATGGCAGGAATCGGGGCCTGTGGGGAGAAGGG TCCAGGCCTCTCGTTTTAGGGACTGATTCCTGGTTTGTTCAGTTCTTAGTCAACTCACCT AATCATACGTGCCAGGAAATTCCCATGTTTTCTGTAGTTTTAGTTTTAGTTTTTTTTTTT TTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCCAGACTGGAGTGCAGTCCTGGCG CGATCTGGGGTCACTGTAACCTTCACCTCCCAGGTTCAAGCAATTCTCCCACCTCAGCCT TCTGAGTAGCTGGGATTACAGGCATCCACCACCATGCCCAGCTAATTTTTGTATTTTTGT AGAGACGGAGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCC TCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCCTGGCTGCT GTTGCTGTTTGTTTTTAAGCCAATCTACAGACATGTCTTGTAACAGGGACAAAATATTCC TTAAAGTGGCCAAAAGCCAGCTGAACAGGAAGTGCCCCCTATGTGACCAGTGGGCAGTTC AGAGTCTAGGGCATGGATCTCCAGCTTCCCCAGGCTTGCTCAGACCCCTCTCTGACCTCT CCTCTGCCCAGGTCCCCCCAGCGAACCCACCCACCTGGCAGTAGAGGACGTCTCTGACAC CACGGTCTCCCTCAAGTGGCGGCCCCCAGAGCGCGTGGGAGCAGGAGGCCTGGATGGCTA CAGCGTGGAGTACTGCCCAGAGGGCTGTGAGTGTCCCCGCCCCCAACCCCCCTCCCCAAA GGAAGAACATGCTCACCTTGCCATTGAGCAGATTCACCTGTAGTCAAGTTTTTTAGGCCC ACTTTTGCCGAAAGTTGAGGACACCCAGAGAAATATCTGTCCTGTTTTCAGAAGTAAAAA AGCTTGCCTAGTGAAAAACAAATGCAGAGTAAAGCTGACTGTAACACTTCTTTGAGCAGT GCGAAATCAGCAACTACATTTTAAAAACATATTTAAGGCCAGGCGCGATGGCTTACGCCT GTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCGGATCACCTGAGGTCGGGAGTTCGAGA CCAGTCTGACCAACGTGGAGAAACCCCGTCTCTACTAAAAATACAAAATTAGCCGGGTGT GGTGGTGGGCACCTGTGATCCCAGCTACGCGGGAGGCTGAGGCAGGAGAATCACTTGAAC TCGGGAGGCAGAAGTTGCGGTGAGCCAAGATCATGCCATTGCACTCCAGCCTGGGAGACA AGAGCGAAACTCCATCTCAAAAATAAATAAACAAATAAAAATTTAAAAAAACATATTTAA ATCCTGGAGATTCCTATCAGAGGAGTGGGCAGTGGGAGTGGGGTGTCAGTGGTGACACAG CCTGTGGCCTTGCCTCCCCCTCCCCACCCCCAGGCTCAGAGTGGGTGGCTGCCCTGCAGG GGCTGACAGAGCACACATCGATACTGGTGAAGGACCTGCCCACGGGGGCCCGGCTGCTTT TCCGAGTGCGGGCACACAATATGGCAGGGCCTGGAGCCCCTGTTACCACCACGGAGCCGG TGACAGTGCAGGAGATCCTGCGTGAGTGCCCCTTTGTGCAGTCACAAGACCCGCCATTGA CACCCCAGGCCCTTGGTGTCCAGTGGAGGTGGGGACAGTTGGGGAGGCCCAGAATGCTCT GCCCAGAACGCTGGGCAGAGACAGGAGGGGTTGGAGCCATCGTCCATGCGCTAGGCCTAG GGAAAAAGTGCAGAGAGGGTGGCCAGGCACAGTGGCTCAAGCCTGTAATCCCAGCACTTT AGGAGGCCAAGGCAGGCAGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACAT AGTGAAACCCTGTCTCTACTAAAAATACAAAAACTAGCCAGGTGTGGTGGCGCGTGCCTG TAGTCCCTCAACTACTTGGGAGGCTGAGGCAGAAGAATCGCTTGGACCCGGGAGGTGGCA GTTGCAATGAGCTGAGATCACACTATTGCACTCCAGTCTGGGTGACAGAGTGAGACAACG TCTCAAAAAAAAAAAAAGTGCAGAAAGGGCTCTCTTGGTGTATGTCAGTCCCTTAGTTCT GGAACAGGGAAAGTAAAAGCCACAGTACCCAAGCTCTCTTCCAGGAGTGTCTCAGCTCCA ACAGGTAAATATTGTCTATGTAGTCAGATTGGTCCCTCTGGGATCCACTTCCCATTCCTT TGTTCCTTGTCCCAACAAAGGGTCCATCTTTTGTAAGGATTGGTTCTCAAAGCTGGAACG AGGCAGCAAACTCAGGTGGTAACAACACAGGGCATAGGGTGTCAAAGCCCAGGCTTACAC CCTGGTCTATGACTTACTAGCTGTGTGACTTCAGTCAAGTTGCTTACCCTCTCTGATCCC TGCCTTTTGAAGTGGTGAGGCTCGGGGAAGCCAGCTGGGCTTGGGCAGCCTGGAGTTGCT GTGTTAGCAGGAGCTAAAGGAGGCGCAGGGCCCAGCAGGCAGCTTTTTTCTTAGCTGCAG CTCTCTGGGCCTTGTCTCAAGGGAGGTTGGAGCTGTGGAGCCCCTCAGAGCTGTGGCGGG CCCTCACTTAGCTACCCACTCTATACCCACAGAACGGCCACGGCTTCAGCTGCCCAGGCA CCTGCGCCAGACCATTCAGAAGAAGGTCGGGGAGCCTGTGAACCTTCTCATCCCTTTCCA GGTGGGACTGGCCCCCTTCCCTGTCCCCCAGGGGAGAGAGGCTATAGTGTGTTGTTCCCA TCCAGTGGACTGATGTCTCAGGGCTGGCCTGATCTGAGGTACCAGAGGCTGGGGTGGCGG CCGGCCCTTGGAGTGATCCAGGTTCAGGGTTAAGCTTTTCCTCCCCTCAGGGCAAGCCCC GGCCTCAGGTGACCTGGACCAAAGAGGGGCAGCCCCTGGCAGGCGAGGAGGTGAGCATCC GCAACAGCCCCACAGACACCATCCTGTTCATCCGGGCCGCTCGCCGCGTGCATTCAGGCA CTTACCAGGTGACGGTGCGCATTGAGAACATGGAGGACAAGGCCACGCTGGTGCTGCAGG TTGTTGGTGCGTGGCCAAGGCCTCCTTGAGCCCCCTTGTTTCCCTTCCCTGGGCTGGGCT GCTGGGGCCAAGGGTGGGGCCAGGGGACCCAACCCACAGCTCACATTTTCCAGTCCACTG CCCCAGCAGGCCTGGCCCTGGTTGGCAGGGGTGGGGTGGTCCCTGGAGCCAGTGACCCCC TGCTCACTGTCAGGAGGCGTGGTGACCCAACTGGGTCTGTCTCCCGCAGACAAGCCAAGT CCTCCCCAGGATCTCCGGGTGACTGACGCCTGGGGTCTTAATGTGGCTCTGGAGTGGAAG CCACCCCAGGATGTCGGCAACACGGAGCTCTGGGGGTACACAGTGCAGAAAGCCGACAAG AAGACCATGGTGAGCCCAGGGTCTGGGGTCCCCACGTGCACCCTGCCTAGGCCCGGCAGA CCCAGGCCGCAGCTACCCTTCACTGTCCTCACCGTGGACCCCTCACCCTCCCTCTGCTGA TCTGAATCCCTCCATAGTAGGGGTGGAGATGCCAAGGGCACCCAGGAGAGGCTCTCGGCA TCAGGAAGGGCCTGGCCCAGAGATGCCTCCCCTCCCTCCCTGCCCCCAGGAGTGGTTCAC CGTCTTGGAGCATTACCGCCGCACCCACTGCGTGGTGCCAGAGCTCATCATTGGCAATGG CTACTACTTCCGCGTCTTCAGCCAGAATATGGTTGGCTTTAGTGACAGAGCGGCCACCAC CAAGGAGCCCGTCTTTATCCCCAGACCAGGTGCTGTACCCTCATTCTTCCAACCAGGGGC TGGGGCAGGGAGGCTGTGGGAACAGGGAGAGGGGCCTAGCTTTGTGTGGCCCTCTCGGTA CCAAGTCCTGTCACCAACAGGCATCACCTATGAGCCACCCAACTATAAGGCCCTGGACTT CTCCGAGGCCCCAAGCTTCACCCAGCCCCTGGTGAACCGCTCGGTCATCGCGGGCTACAC TGCTATGCTCTGCTGTGCTGTCCGGGGTAGCCCCAAGGTAGGGAACTTTAGGCGCTGGTC CAGGCCGACCAGGAGGCAGGGCTCACAGGCCCCGACGTTGAGCAGTCCTCTCCCCAGCCT GTCTCCCCTGCTTTCTCTCCACCTTGGGGTGTATGGACCGGGTTCCTCCCCCTGGGCAGG GCCATGGTACTCACTCTTGGTTCCATGTTTGTTTCCAGCCTTGGGCATAGTCAGGGACTC TCGTGGGACCCCCCGAGTAGAAACACAGATGTGTCTCCCTGGGTCCCTGCCAGGTCCCCT CTCAGCCTGGATGGCTTCCCTCCCTCTCTTTACCTTATTTATAGCCCAAGATTTCCTGGT TCAAGAATGGCCTGGACCTGGGAGAAGACGCCCGCTTCCGCATGTTCAGCAAGCAGGGAG TGTTGACTCTGGAGATTAGAAAGCCCTGCCCCTTTGACGGGGGCATCTATGTCTGCAGGG CCACCAACTTACAGGGCGAGGCACGGTGTGAGTGCCGCCTGGAGGTGCGAGGTGAGGAGC CCTCGGGGCCAGGGCCTGGGAGATGGGAAGAGCGGGCGGCAGTGGGGACCCTGGGCTTTG CTCCGTTGTCCTCGGCCAAGCACCTGCCCTGGCTGCAAGGGCACGGACCCTGCCACGCCC AGATGGGCAATAGCTTCCAGAAGGCTGGGAGGACACAGTGACATGGCCTCCTCTTCTGCA GTGCCTCAGTGACCAGGCTGGCTCCTGGGGATGGCCAGGTATGTACCACCCGACACCCAG GGCACAAGTCAGTGGCTGAGCCCTGGCCCTTGGTCCTGGGGCAGCCATCAGTAAATGGGA GGCTGTAGGGGCCCTCCATTCACTCGTAAGATAACCTGTGTTGCAGGTACAACCGGATGC CAGCCCCGTGCCAGGAGCCTGGAGGGAAGTTGGGGAAACCCCTCCCTACTGTTGGATGTA TGTGTGACAAGTGTGTCTCCTGTGCTGCGATGGGGGATCAGCAGGGCAGTTGTCGGGCAG TCCTGAGTGGGTGTTGCACAGACTGGTCCACAGGGCTCCTGAAGGAAGCCCCTGGATCTT TGGGGTAAAAGGAGGGTGGCCTCAAGAAACAATGTCTGGGGACAGGCCTTTCTGGCCTGC TATGTCTTCCCAATGTTTATTGGGCAATAAAAGATAAGTGCAGTCACAGAGAACTCA OMIM ID 600958