Entrez gene ID | | 4650 |
Official gene symbol | | MYO9B |
Full name | | myosin IXB |
Aliases | | ,CELIAC4,MYR5, |
Gene summary | | This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19p13.1 |
Gene position | | 17186591 - 17324104 Map Viewer |
Gene orientation | | plus |
Gene size | | 137514 bp |
Gene sequence |
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OMIM ID | | 602129 |
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