Entrez gene ID | | 4653 |
Official gene symbol | | MYOC |
Full name | | myocilin, trabecular meshwork inducible glucocorticoid response |
Aliases | | ,GLC1A,GPOA,JOAG,JOAG1,TIGR,myocilin, |
Gene summary | | MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q23-q24 |
Gene position | | 171621773 - 171604557 Map Viewer |
Gene orientation | | minus |
Gene size | | 17217 bp |
Gene sequence |
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OMIM ID | | 601652 |
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