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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PPP1R12B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4660
Official gene symbolPPP1R12B
Full nameprotein phosphatase 1, regulatory (inhibitor) subunit 12B
Aliases,FLJ40942,MGC131980,MGC87886,MYPT2,
Gene summarySummary: Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q32.1
Gene position202317830 - 202557697  Map Viewer
Gene orientationplus
Gene size239868 bp
Gene sequence
OMIM ID603768