Entrez gene ID | | 4681 |
Official gene symbol | | NBL1 |
Full name | | neuroblastoma, suppression of tumorigenicity 1 |
Aliases | | ,D1S1733E,DAN,DAND1,MGC8972,NB,NO3, |
Gene summary | | This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p36.13 |
Gene position | | 19969726 - 19984945 Map Viewer |
Gene orientation | | plus |
Gene size | | 15220 bp |
Gene sequence |
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OMIM ID | | 600613 |
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