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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NEK3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4752
Official gene symbolNEK3
Full nameNIMA (never in mitosis gene a)-related kinase 3
Aliases,HSPK36,MGC29949,
Gene summaryThis gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.
LocationChromosome: 13   Locus: 13q14.13
Gene position52733996 - 52706779  Map Viewer
Gene orientationminus
Gene size27218 bp
Gene sequence
OMIM ID604044