Entrez gene ID | | 4773 |
Official gene symbol | | NFATC2 |
Full name | | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
Aliases | | ,NFAT1,NFATP, |
Gene summary | | This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20q13.2-q13.3 |
Gene position | | 50179168 - 50007765 Map Viewer |
Gene orientation | | minus |
Gene size | | 171404 bp |
Gene sequence |
| |
OMIM ID | | 600490 |
|