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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NFYA (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4800
Official gene symbolNFYA
Full namenuclear transcription factor Y, alpha
Aliases,CBF-A,CBF-B,FLJ11236,HAP2,NF-YA,
Gene summaryThe protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq]
LocationChromosome: 6   Locus: 6p21.3
Gene position41040707 - 41070146  Map Viewer
Gene orientationplus
Gene size29440 bp
Gene sequence
OMIM ID189903