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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NFYB (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4801
Official gene symbolNFYB
Full namenuclear transcription factor Y, beta
Aliases,CBF-A,CBF-B,HAP3,NF-YB,
Gene summaryThe protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q22-q23
Gene position104532040 - 104510858  Map Viewer
Gene orientationminus
Gene size21183 bp
Gene sequence
OMIM ID189904