| Entrez gene ID | | 483 |
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| Official gene symbol | | ATP1B3 |
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| Full name | | ATPase, Na+/K+ transporting, beta 3 polypeptide |
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| Aliases | | ,ATPB-3,CD298,FLJ29027, |
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| Gene summary | | The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq] |
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| Location | | Chromosome: 3 Locus: 3q23 |
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| Gene position | | 141595470 - 141645382 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 49913 bp |
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| Gene sequence |
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| OMIM ID | | 601867 |
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