Entrez gene ID | | 4852 |
Official gene symbol | | NPY |
Full name | | neuropeptide Y |
Aliases | | ,PYY4, |
Gene summary | | This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. [provided by RefSeq] |
Location | | Chromosome: 7 Locus: 7p15.1 |
Gene position | | 24323807 - 24331484 Map Viewer |
Gene orientation | | plus |
Gene size | | 7678 bp |
Gene sequence |
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OMIM ID | | 162640 |
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