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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NPPA (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 4878 Official gene symbol NPPA Full name natriuretic peptide precursor A Aliases ,ANF,ANP,ATFB6,CDD-ANF,PND, Gene summary The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq] Location Chromosome: 1   Locus: 1p36.21 Gene position 11907840 - 11905766  Map Viewer Gene orientation minus Gene size 2075 bp Gene sequence >NPPA:complement(7910498..7912572):Length=2075 GAGACAGGGACAGACGTAGGCCAAGAGAGGGGAACCAGAGAGGAACCAGAGGGGAGAGAC AGAGCAGCAAGCAGTGGATTGCTCCTTGACGACGCCAGCATGAGCTCCTTCTCCACCACC ACCGTGAGCTTCCTCCTTTTACTGGCATTCCAGCTCCTAGGTCAGACCAGAGCTAATCCC ATGTACAATGCCGTGTCCAACGCAGACCTGATGGATTTCAAGGTAGGGCCAGGAAAGCGG GTGCAGTCTGGGGCCAGGGGGCTTTCTGATGCTGTGCTCACTCCTCTTGATTTCCTCCAA GTCAGTGAGGTTTATCCCTTTCCCTGTATTTTCCTTTTCTAAAGAATTTGCTGGACCATT TGGAAGAAAAGATGCCTTTAGAAGATGAGGTCGTGCCCCCACAAGTGCTCAGTGAGCCGA ATGAAGAAGCGGGGGCTGCTCTCAGCCCCCTCCCTGAGGTGCCTCCCTGGACCGGGGAAG TCAGCCCAGCCCAGAGAGATGGAGGTGCCCTCGGGCGGGGCCCCTGGGACTCCTCTGATC GATCTGCCCTCCTAAAAAGCAAGCTGAGGGCGCTGCTCACTGCCCCTCGGAGCCTGCGGA GATCCAGCTGCTTCGGGGGCAGGATGGACAGGATTGGAGCCCAGAGCGGACTGGGCTGTA ACAGCTTCCGGGTAAGAGGAACTGGGGATGGAAATGGGATGGGATGGACACTACTGGGAG ACACCTTCAGCAGGAAAGGGACCAATGCAGAAGCTCATTCCCTCTCAAGTTTCTGCCCCA ACACCCAGAGTGCCCCATGGGTGTCAGGACATGCCATCTATTGTCCTTAGCTAGTCTGCT GAGAAAATGCTTAAAAAAAAAAGGGGGGGGGGCTGGGCACAGTGGCTCACGCCTGTAATC CCAGCACTTTGGGAGGCCGAGGCAGGCGGATCATGAGGTCAAGAGATCAAGACTATCCTG GCCAACATGGTGAAACCCCAGCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCG GGCACCTGTACTCTCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGAG GCAGAGGTTGCAGTGAGCAGAGATCACGCCACTGCAGTCCAGCCTAGGTGATAGAGCGAG ACTGTCTCAAAAAAAAAAAAAAAAGGCCAGGCACGGTGGCTCACGCCTGTAATCCCAGCG CTTTGGGAGGCCAAGGCGGGTGGATCACGAGGTCAGGAGATGGAGACCATCCTGGCTAAC ACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGCAGGCGC CTGTAAGTCCTAGCTACTCCGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGG AGCTTGCAGTGAGCAGAGATGGCACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTC CGTCTCAAAAAAAAAAAAAAAAAAAGCAACTGCCACTAGCACTGGGAAATTAAAATATTC ATAGAGCCAAGTTATCTTTGCATGGCTGATTAGCAGTTCATATTCCTCCCCAGAATTGCA AGATCCTGAAGGGCTTAAGTGAAATTTACTCTGATGAGTAACTTGCTTATCAATTCATGA AGCTCAGAGGGTCATCAGGCTGGGGTGGGGGCCGGTGGGAAGCAGGTGGTCAGTAATCAA GTTCAGAGGATGGGCACACTCATACATGAAGCTGACTTTTCCAGGACAGCCAGGTCACCA AGCCAGATATGTCTGTGTTCTCTTTGCAGTACTGAAGATAACAGCCAGGGAGGACAAGCA GGGCTGGGCCTAGGGACAGACTGCAAGAGGCTCCTGTCCCCTGGGGTCTCTGCTGCATTT GTGTCATCTTGTTGCCATGGAGTTGTGATCATCCCATCTAAGCTGCAGCTTCCTGTCAAC ACTTCTCACATCTTATGCTAACTGTAGATAAAGTGGTTTGATGGTGACTTCCTCGCCTCT CCCACCCCATGCATTAAATTTTAAGGTAGAACCTCACCTGTTACTGAAAGTGGTTTGAAA GTGAATAAACTTCAGCACCATGGACAGAAGACAAA OMIM ID 108780