Entrez gene ID | | 4899 |
Official gene symbol | | NRF1 |
Full name | | nuclear respiratory factor 1 |
Aliases | | ,ALPHA-PAL, |
Gene summary | | This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq] |
Location | | Chromosome: 7 Locus: 7q32 |
Gene position | | 129251555 - 129396922 Map Viewer |
Gene orientation | | plus |
Gene size | | 145368 bp |
Gene sequence |
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OMIM ID | | 600879 |
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