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Gene information for NRGN (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4900
Official gene symbolNRGN
Full nameneurogranin (protein kinase C substrate, RC3)
Aliases,RC3,hng,
Gene summaryNeurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q24
Gene position124609829 - 124617102  Map Viewer
Gene orientationplus
Gene size7274 bp
Gene sequence
OMIM ID602350