Entrez gene ID | | 4915 |
Official gene symbol | | NTRK2 |
Full name | | neurotrophic tyrosine kinase, receptor, type 2 |
Aliases | | ,GP145-TrkB,TRKB, |
Gene summary | | This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 9 Locus: 9q22.1 |
Gene position | | 87283466 - 87638505 Map Viewer |
Gene orientation | | plus |
Gene size | | 355040 bp |
Gene sequence |
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OMIM ID | | 600456 |
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