Entrez gene ID | | 4946 |
Official gene symbol | | OAZ1 |
Full name | | ornithine decarboxylase antizyme 1 |
Aliases | | ,AZI,MGC138338,OAZ, |
Gene summary | | Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase and accelerates its degradation. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19p13.3 |
Gene position | | 2269520 - 2273487 Map Viewer |
Gene orientation | | plus |
Gene size | | 3968 bp |
Gene sequence |
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OMIM ID | | 601579 |
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