Entrez gene ID | | 4947 |
Official gene symbol | | OAZ2 |
Full name | | ornithine decarboxylase antizyme 2 |
Aliases | | ,AZ2, |
Gene summary | | Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase but does not accelerate its degradation. [provided by RefSeq] |
Location | | Chromosome: 15 Locus: 15q22.31 |
Gene position | | 64995462 - 64979773 Map Viewer |
Gene orientation | | minus |
Gene size | | 15690 bp |
Gene sequence |
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OMIM ID | | 604152 |