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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for OPCML (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4978
Official gene symbolOPCML
Full nameopioid binding protein/cell adhesion molecule-like
Aliases,IGLON1,OBCAM,OPCM,
Gene summaryThis gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q25
Gene position133402403 - 132284875  Map Viewer
Gene orientationminus
Gene size1117529 bp
Gene sequence
OMIM ID600632