| Entrez gene ID | | 5020 |
|
| Official gene symbol | | OXT |
|
| Full name | | oxytocin, prepropeptide |
|
| Aliases | | ,MGC126890,MGC126892,OT,OT-NPI, |
|
| Gene summary | | There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq] |
|
| Location | | Chromosome: 20 Locus: 20p13 |
|
| Gene position | | 3052266 - 3053162 Map Viewer |
|
| Gene orientation | | plus |
|
| Gene size | | 897 bp |
|
| Gene sequence |
| |
|
| OMIM ID | | 167050 |
|
|
|
