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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PARK2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5071
Official gene symbolPARK2
Full nameParkinson disease (autosomal recessive, juvenile) 2, parkin
Aliases,AR-JP,LPRS2,PDJ,PRKN,
Gene summaryThe precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q25.2-q27
Gene position163148834 - 161768590  Map Viewer
Gene orientationminus
Gene size1380245 bp
Gene sequence
OMIM ID602544