Entrez gene ID | | 51081 |
Official gene symbol | | MRPS7 |
Full name | | mitochondrial ribosomal protein S7 |
Aliases | | ,MRP-S,MRP-S7,RP-S7,RPMS7,S7mt,bMRP27a, |
Gene summary | | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in organizing the 3' domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q25 |
Gene position | | 73257749 - 73262457 Map Viewer |
Gene orientation | | plus |
Gene size | | 4709 bp |
Gene sequence |
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OMIM ID | | 611974 |
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